Plasma Plasmodium falciparum histidine-rich protein-2 concentrations are associated with malaria severity and mortality in Tanzanian children.

Plasma Plasmodium falciparum histidine-rich protein-2 concentrations are associated with malaria severity and mortality in Tanzanian children.

Plasma Plasmodium falciparum histidine-rich protein-2 (PfHRP-2) concentrations, a measure of parasite biomass, have been correlated with malaria severity in adults, but not yet in children. We measured plasma PfHRP-2 in Tanzanian children with uncomplicated (n = 61) and cerebral malaria (n = 45; 7 d...

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Main Authors: Matthew P Rubach, Jackson Mukemba, Salvatore Florence, Bernard John, Benjamin Crookston, Bert K Lopansri, Tsin W Yeo, Kim A Piera, Stephen C Alder, J Brice Weinberg, Nicholas M Anstey, Donald L Granger, Esther D Mwaikambo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3346811?pdf=render

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