Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population

Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population

Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by dietary, environmental, and genetic factors. While the incidence of IBD is increasing worldwide, we still lack a complete understanding of the gene-by-environment interactions underlying inflammation and IBD....

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Bibliographic Details
Main Authors: Xiaoxu Li, Jean-David Morel, Giorgia Benegiamo, Johanne Poisson, Alexis Bachmann, Alexis Rapin, Jonathan Sulc, Evan Williams, Alessia Perino, Kristina Schoonjans, Maroun Bou Sleiman, Johan Auwerx
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
BXD mice
UK Biobank
systems genetics
inflammatory bowel disease (IBD)
high-fat diet
module quantitative trait locus (ModQTL) mapping
Online Access:https://elifesciences.org/articles/87569

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