ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.

ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.

ZBED6 is a recently discovered transcription factor, unique to placental mammals, that has evolved from a domesticated DNA transposon. It acts as a repressor at the IGF2 locus. Here we show that ZBED6 acts as a transcriptional modulator in mouse myoblast cells, where more than 700 genes were differe...

Full description

Bibliographic Details
Main Authors: Lin Jiang, Ola Wallerman, Shady Younis, Carl-Johan Rubin, Elizabeth R Gilbert, Elisabeth Sundström, Awaisa Ghazal, Xiaolan Zhang, Li Wang, Tarjei S Mikkelsen, Göran Andersson, Leif Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979763?pdf=render

Similar Items

Similar Items