In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes

In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes

Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors, and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α-amylase enzymes inhibitors can suppress peaks of postprandial glucose with surplus adverse effects, leading to effort...

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Bibliographic Details
Main Authors: Jirawat Riyaphan, Dinh-Chuong Pham, Max K. Leong, Ching-Feng Weng
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
polyphenol
in silico
herb medicine
type II diabetes
Online Access:https://www.mdpi.com/2218-273X/11/12/1877

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