New management strategies for primary headache disorders: Insights from P4 medicine
Primary headache disorder is the main cause of headache attacks, leading to significant disability and impaired quality of life. This disorder is increasingly recognized as a heterogeneous condition with a complex network of genetic, environmental, and lifestyle factors. However, the timely diagnosi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023094938 |
| _version_ | 1827615804766552064 |
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| author | Yu Zhang Wanbin Huang Songqing Pan Zhengming Shan Yanjie Zhou Quan Gan Zheman Xiao |
| author_facet | Yu Zhang Wanbin Huang Songqing Pan Zhengming Shan Yanjie Zhou Quan Gan Zheman Xiao |
| author_sort | Yu Zhang |
| collection | DOAJ |
| description | Primary headache disorder is the main cause of headache attacks, leading to significant disability and impaired quality of life. This disorder is increasingly recognized as a heterogeneous condition with a complex network of genetic, environmental, and lifestyle factors. However, the timely diagnosis and effective treatment of these headaches remain challenging. Precision medicine is a potential strategy based on P4 (predictive, preventive, personalized, and participatory) medicine that may bring new insights for headache care. Recent machine learning advances and widely available molecular biology and imaging data have increased the usefulness of this medical strategy. Precision medicine emphasizes classifying headaches according to their risk factors, clinical presentation, and therapy responsiveness to provide individualized headache management. Furthermore, early preventive strategies, mainly utilizing predictive tools, are critical in reducing headache attacks and improving the quality of life of individuals with headaches. The current review comprehensively discusses the potential application value of P4 medicine in headache management. |
| first_indexed | 2024-03-09T09:16:57Z |
| format | Article |
| id | doaj.art-8beae1183b8c4573ab83b5ae4c2bcff5 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-09T09:16:57Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-8beae1183b8c4573ab83b5ae4c2bcff52023-12-02T07:05:39ZengElsevierHeliyon2405-84402023-11-01911e22285New management strategies for primary headache disorders: Insights from P4 medicineYu Zhang0Wanbin Huang1Songqing Pan2Zhengming Shan3Yanjie Zhou4Quan Gan5Zheman Xiao6Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaCorresponding author.; Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaPrimary headache disorder is the main cause of headache attacks, leading to significant disability and impaired quality of life. This disorder is increasingly recognized as a heterogeneous condition with a complex network of genetic, environmental, and lifestyle factors. However, the timely diagnosis and effective treatment of these headaches remain challenging. Precision medicine is a potential strategy based on P4 (predictive, preventive, personalized, and participatory) medicine that may bring new insights for headache care. Recent machine learning advances and widely available molecular biology and imaging data have increased the usefulness of this medical strategy. Precision medicine emphasizes classifying headaches according to their risk factors, clinical presentation, and therapy responsiveness to provide individualized headache management. Furthermore, early preventive strategies, mainly utilizing predictive tools, are critical in reducing headache attacks and improving the quality of life of individuals with headaches. The current review comprehensively discusses the potential application value of P4 medicine in headache management.http://www.sciencedirect.com/science/article/pii/S2405844023094938MigraineTension-type headacheCluster headachePersonalized managementPrecision medicine |
| spellingShingle | Yu Zhang Wanbin Huang Songqing Pan Zhengming Shan Yanjie Zhou Quan Gan Zheman Xiao New management strategies for primary headache disorders: Insights from P4 medicine Heliyon Migraine Tension-type headache Cluster headache Personalized management Precision medicine |
| title | New management strategies for primary headache disorders: Insights from P4 medicine |
| title_full | New management strategies for primary headache disorders: Insights from P4 medicine |
| title_fullStr | New management strategies for primary headache disorders: Insights from P4 medicine |
| title_full_unstemmed | New management strategies for primary headache disorders: Insights from P4 medicine |
| title_short | New management strategies for primary headache disorders: Insights from P4 medicine |
| title_sort | new management strategies for primary headache disorders insights from p4 medicine |
| topic | Migraine Tension-type headache Cluster headache Personalized management Precision medicine |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023094938 |
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