Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei
In the present investigation, an antihyperlipidemic activity of Cladophora koeiei ethanol extract against six pathogenic bacteria was conducted. Also, we evaluate the activity of the alga extract against hyperlipedemia in the administrated albino rates through measuring the blood lipid profiles [tri...
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| Format: | Article |
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SpringerOpen
2018-03-01
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| Series: | Beni-Suef University Journal of Basic and Applied Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2314853517301828 |
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| author | Neveen Abdel-Raouf Nouf Mohammed Al-Enazi Ibraheem Borie Mohammad Ibraheem Reem Mohammed Alharbi Manal Mohammed Alkhulaifi |
| author_facet | Neveen Abdel-Raouf Nouf Mohammed Al-Enazi Ibraheem Borie Mohammad Ibraheem Reem Mohammed Alharbi Manal Mohammed Alkhulaifi |
| author_sort | Neveen Abdel-Raouf |
| collection | DOAJ |
| description | In the present investigation, an antihyperlipidemic activity of Cladophora koeiei ethanol extract against six pathogenic bacteria was conducted. Also, we evaluate the activity of the alga extract against hyperlipedemia in the administrated albino rates through measuring the blood lipid profiles [triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein cholesterol (HDL-C), cholesterol] and induced hepatic damage by measuring the contents of creatinine, total proteins, blood urea nitrogen (BUN), albumin and globulin and diagnostic marker enzymes such as aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT). Alga extract proved efficient activity against the tested bacteria ranged between medium and high suppression action. Results revealed also, the efficiency of C. koeiei extract in the decreasing the triglycerides (TG), total cholesterol (TC), low-density lipoproteins (LDL-C), blood urea nitrogen (BUN) and creatinine caused by alcohol. However, the treatment by alga extract exhibits high-density of lipoproteins (HDL-C) (beneficial), total protein, albumin, and globulins. Also, the algal treatments masking the lethal effects caused by harmful alcohol from raising the rate of enzymes ALT, AST, which returned to the normal state in the groups treated with alga extract. Our findings provide the evidence that new natural antioxidant substances can be present in the C. koeiei extract and hence this alga proves to be effective as a source for therapeutic agents. |
| first_indexed | 2024-12-10T16:05:35Z |
| format | Article |
| id | doaj.art-8beda3c2788c404c87165f5341c34b9f |
| institution | Directory Open Access Journal |
| issn | 2314-8535 |
| language | English |
| last_indexed | 2024-12-10T16:05:35Z |
| publishDate | 2018-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Beni-Suef University Journal of Basic and Applied Sciences |
| spelling | doaj.art-8beda3c2788c404c87165f5341c34b9f2022-12-22T01:42:15ZengSpringerOpenBeni-Suef University Journal of Basic and Applied Sciences2314-85352018-03-017115816410.1016/j.bjbas.2017.10.002Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeieiNeveen Abdel-Raouf0Nouf Mohammed Al-Enazi1Ibraheem Borie Mohammad Ibraheem2Reem Mohammed Alharbi3Manal Mohammed Alkhulaifi4Botany and Microbiology Department, Faculty of Science, Beni-Suef University, EgyptBiology Department, College of Science and Humanity Studies, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi ArabiaBotany and Microbiology Department, Faculty of Science, Beni-Suef University, EgyptBiology Department, College of Education, Dammam University, Hafer Al-Baten, Saudi ArabiaBotany & Microbiology Department, Science College, King Saud University, Saudi ArabiaIn the present investigation, an antihyperlipidemic activity of Cladophora koeiei ethanol extract against six pathogenic bacteria was conducted. Also, we evaluate the activity of the alga extract against hyperlipedemia in the administrated albino rates through measuring the blood lipid profiles [triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein cholesterol (HDL-C), cholesterol] and induced hepatic damage by measuring the contents of creatinine, total proteins, blood urea nitrogen (BUN), albumin and globulin and diagnostic marker enzymes such as aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT). Alga extract proved efficient activity against the tested bacteria ranged between medium and high suppression action. Results revealed also, the efficiency of C. koeiei extract in the decreasing the triglycerides (TG), total cholesterol (TC), low-density lipoproteins (LDL-C), blood urea nitrogen (BUN) and creatinine caused by alcohol. However, the treatment by alga extract exhibits high-density of lipoproteins (HDL-C) (beneficial), total protein, albumin, and globulins. Also, the algal treatments masking the lethal effects caused by harmful alcohol from raising the rate of enzymes ALT, AST, which returned to the normal state in the groups treated with alga extract. Our findings provide the evidence that new natural antioxidant substances can be present in the C. koeiei extract and hence this alga proves to be effective as a source for therapeutic agents.http://www.sciencedirect.com/science/article/pii/S2314853517301828Antibacterial activityAnti-hyperlipidemicCladophora koeiei |
| spellingShingle | Neveen Abdel-Raouf Nouf Mohammed Al-Enazi Ibraheem Borie Mohammad Ibraheem Reem Mohammed Alharbi Manal Mohammed Alkhulaifi Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei Beni-Suef University Journal of Basic and Applied Sciences Antibacterial activity Anti-hyperlipidemic Cladophora koeiei |
| title | Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei |
| title_full | Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei |
| title_fullStr | Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei |
| title_full_unstemmed | Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei |
| title_short | Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei |
| title_sort | antibacterial and anti hyperlipidemic activities of the green alga cladophora koeiei |
| topic | Antibacterial activity Anti-hyperlipidemic Cladophora koeiei |
| url | http://www.sciencedirect.com/science/article/pii/S2314853517301828 |
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