Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clusters

Abstract Chromatin state is thought to impart regulatory function to the underlying DNA sequence. This can be established through histone modifications and chromatin organisation, but exactly how these factors relate to one another to regulate gene expression is unclear. In this study, we have used...

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Bibliographic Details
Main Authors: Stefan A. Koestler, Madeleine L. Ball, Leila Muresan, Vineet Dinakaran, Robert White
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-024-00535-9