Inositol hexaphosphate-induced cellular response in myeloid leukemia cells is mediated by nicotinamide adenine dinucleotide phosphate oxidase activation

Inositol hexaphosphate-induced cellular response in myeloid leukemia cells is mediated by nicotinamide adenine dinucleotide phosphate oxidase activation

Objectives: The objective of this study was to identify the role of reactive oxygen species (ROS) generated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, in inositol hexaphosphate (IP6)-induced metabolic disruption in human leukemia PLB-985 cells. Methods: PLB-985 and X chromosome...

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Bibliographic Details
Main Authors: Asuka Kato, Yuki Hirakawa, Wakako Hiraoka
Format: Article
Language:English
Published: Fujita Medical Society 2019-11-01
Series:Fujita Medical Journal
Subjects:
inositol hexaphosphate
reactive oxygen species
nadph oxidase
x-cgd cells
plb-985 cells
Online Access:https://www.jstage.jst.go.jp/article/fmj/5/4/5_2018-020/_pdf/-char/en

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