Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the most common (90%) type of solid pancreatic neoplasm. Due to its late presentation and poor survival rate, early diagnosis and timely treatment is of utmost importance for better clinical outcomes. Endoscopic ultrasound provides high-resolution images of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/14/1/78 |
| _version_ | 1797358945326596096 |
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| author | Abhirup Chatterjee Jimil Shah |
| author_facet | Abhirup Chatterjee Jimil Shah |
| author_sort | Abhirup Chatterjee |
| collection | DOAJ |
| description | Pancreatic ductal adenocarcinoma (PDAC) is the most common (90%) type of solid pancreatic neoplasm. Due to its late presentation and poor survival rate, early diagnosis and timely treatment is of utmost importance for better clinical outcomes. Endoscopic ultrasound provides high-resolution images of the pancreas and has excellent sensitivity in the diagnosis of even small (<2 cm) pancreatic lesions. Apart from imaging, it also has an advantage of tissue acquisition (EUS fine-needle aspiration, FNA; or fine-needle biopsy, FNB) for definitive diagnoses. EUS-guided tissue acquisition plays a crucial role in genomic and molecular studies, which in today’s era of personalized medicine, are likely to become important components of PDAC management. With the use of better needle designs and technical advancements, EUS has now become an indispensable tool in the management of PDAC. Lastly, artificial intelligence for the detection of pancreatic lesions and newer automated needles for tissue acquisition will obviate observer dependency in the near future, resulting in the wider dissemination and adoption of this technology for improved outcomes in patients with PDAC. |
| first_indexed | 2024-03-08T15:09:30Z |
| format | Article |
| id | doaj.art-8bf1d0d747d94c38bc46f99732374e23 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-08T15:09:30Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-8bf1d0d747d94c38bc46f99732374e232024-01-10T14:53:54ZengMDPI AGDiagnostics2075-44182023-12-011417810.3390/diagnostics14010078Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal AdenocarcinomaAbhirup Chatterjee0Jimil Shah1Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, IndiaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, IndiaPancreatic ductal adenocarcinoma (PDAC) is the most common (90%) type of solid pancreatic neoplasm. Due to its late presentation and poor survival rate, early diagnosis and timely treatment is of utmost importance for better clinical outcomes. Endoscopic ultrasound provides high-resolution images of the pancreas and has excellent sensitivity in the diagnosis of even small (<2 cm) pancreatic lesions. Apart from imaging, it also has an advantage of tissue acquisition (EUS fine-needle aspiration, FNA; or fine-needle biopsy, FNB) for definitive diagnoses. EUS-guided tissue acquisition plays a crucial role in genomic and molecular studies, which in today’s era of personalized medicine, are likely to become important components of PDAC management. With the use of better needle designs and technical advancements, EUS has now become an indispensable tool in the management of PDAC. Lastly, artificial intelligence for the detection of pancreatic lesions and newer automated needles for tissue acquisition will obviate observer dependency in the near future, resulting in the wider dissemination and adoption of this technology for improved outcomes in patients with PDAC.https://www.mdpi.com/2075-4418/14/1/78PDACEUSfine-needle aspiration (FNA)fine-needle biopsy (FNB)precision medicinepancreatic carcinoma |
| spellingShingle | Abhirup Chatterjee Jimil Shah Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma Diagnostics PDAC EUS fine-needle aspiration (FNA) fine-needle biopsy (FNB) precision medicine pancreatic carcinoma |
| title | Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma |
| title_full | Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma |
| title_fullStr | Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma |
| title_full_unstemmed | Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma |
| title_short | Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma |
| title_sort | role of endoscopic ultrasound in diagnosis of pancreatic ductal adenocarcinoma |
| topic | PDAC EUS fine-needle aspiration (FNA) fine-needle biopsy (FNB) precision medicine pancreatic carcinoma |
| url | https://www.mdpi.com/2075-4418/14/1/78 |
| work_keys_str_mv | AT abhirupchatterjee roleofendoscopicultrasoundindiagnosisofpancreaticductaladenocarcinoma AT jimilshah roleofendoscopicultrasoundindiagnosisofpancreaticductaladenocarcinoma |