Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching
Abstract Complications such as slow flow are frequently observed in percutaneous coronary intervention (PCI) with rotational atherectomy (RA). However, it remains unclear whether the high incidence of slow flow results in the high incidence of periprocedural myocardial infarction (PMI), reflecting r...
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| Format: | Article |
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Nature Portfolio
2021-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-90042-8 |
| _version_ | 1823971220005060608 |
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| author | Yusuke Mizuno Kenichi Sakakura Hiroyuki Jinnouchi Yousuke Taniguchi Takunori Tsukui Kei Yamamoto Masaru Seguchi Hiroshi Wada Hideo Fujita |
| author_facet | Yusuke Mizuno Kenichi Sakakura Hiroyuki Jinnouchi Yousuke Taniguchi Takunori Tsukui Kei Yamamoto Masaru Seguchi Hiroshi Wada Hideo Fujita |
| author_sort | Yusuke Mizuno |
| collection | DOAJ |
| description | Abstract Complications such as slow flow are frequently observed in percutaneous coronary intervention (PCI) with rotational atherectomy (RA). However, it remains unclear whether the high incidence of slow flow results in the high incidence of periprocedural myocardial infarction (PMI), reflecting real myocardial damage. The aim of this study was to compare the incidence of PMI between PCI with versus without RA using propensity score-matching. We included 1350 elective PCI cases, which were divided into the RA group (n = 203) and the non-RA group (n = 1147). After propensity score matching, the matched RA group (n = 190) and the matched non-RA group (n = 190) were generated. The primary interest was to compare the incidence of PMI between the matched RA and non-RA groups. Before propensity score matching, the incidence of slow flow and PMI was greater in the RA group than in the non-RA group. After matching, the incidence of slow flow was still greater in the matched RA group than in the matched non-RA group (16.8% vs. 9.5%, p = 0.048). However, the incidence of PMI was similar between the matched RA and matched non-RA group (7.4% vs. 5.3%, p = 0.528, standardized difference: 0.086). In conclusion, although use of RA was associated with greater risk of slow flow, use of RA was not associated with PMI after a propensity score-matched analysis. The fact that RA did not increase the risk of myocardial damage in complex lesions would have an impact on revascularization strategy for severely calcified coronary lesions. |
| first_indexed | 2024-12-18T03:24:17Z |
| format | Article |
| id | doaj.art-8bf60616ae0c4f249b20ebe331821f5c |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-18T03:24:17Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-8bf60616ae0c4f249b20ebe331821f5c2022-12-21T21:22:41ZengNature PortfolioScientific Reports2045-23222021-05-011111910.1038/s41598-021-90042-8Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matchingYusuke Mizuno0Kenichi Sakakura1Hiroyuki Jinnouchi2Yousuke Taniguchi3Takunori Tsukui4Kei Yamamoto5Masaru Seguchi6Hiroshi Wada7Hideo Fujita8Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical UniversityAbstract Complications such as slow flow are frequently observed in percutaneous coronary intervention (PCI) with rotational atherectomy (RA). However, it remains unclear whether the high incidence of slow flow results in the high incidence of periprocedural myocardial infarction (PMI), reflecting real myocardial damage. The aim of this study was to compare the incidence of PMI between PCI with versus without RA using propensity score-matching. We included 1350 elective PCI cases, which were divided into the RA group (n = 203) and the non-RA group (n = 1147). After propensity score matching, the matched RA group (n = 190) and the matched non-RA group (n = 190) were generated. The primary interest was to compare the incidence of PMI between the matched RA and non-RA groups. Before propensity score matching, the incidence of slow flow and PMI was greater in the RA group than in the non-RA group. After matching, the incidence of slow flow was still greater in the matched RA group than in the matched non-RA group (16.8% vs. 9.5%, p = 0.048). However, the incidence of PMI was similar between the matched RA and matched non-RA group (7.4% vs. 5.3%, p = 0.528, standardized difference: 0.086). In conclusion, although use of RA was associated with greater risk of slow flow, use of RA was not associated with PMI after a propensity score-matched analysis. The fact that RA did not increase the risk of myocardial damage in complex lesions would have an impact on revascularization strategy for severely calcified coronary lesions.https://doi.org/10.1038/s41598-021-90042-8 |
| spellingShingle | Yusuke Mizuno Kenichi Sakakura Hiroyuki Jinnouchi Yousuke Taniguchi Takunori Tsukui Kei Yamamoto Masaru Seguchi Hiroshi Wada Hideo Fujita Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching Scientific Reports |
| title | Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching |
| title_full | Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching |
| title_fullStr | Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching |
| title_full_unstemmed | Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching |
| title_short | Comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score-matching |
| title_sort | comparison of the incidence of periprocedural myocardial infarction between percutaneous coronary intervention with versus without rotational atherectomy using propensity score matching |
| url | https://doi.org/10.1038/s41598-021-90042-8 |
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