Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review
Neurulation, as the formation of the basis of the nervous system, is the earliest and crucial stage of embryonic development, affecting the development of other parts of the embryonic body. During neurulation, the neural plate is formed through morphological changes. At the end of this stage, the ne...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Negah Institute for Scientific Communication
2022-08-01
|
| Series: | Anatomical Sciences Journal |
| Subjects: | |
| Online Access: | http://anatomyjournal.ir/article-1-572-en.pdf |
| _version_ | 1797524851675627520 |
|---|---|
| author | Hossein Bahadoran Reza Dadfar Mohammad Hosein Asadi Amir Abdolmaleki Sajad Moghadami |
| author_facet | Hossein Bahadoran Reza Dadfar Mohammad Hosein Asadi Amir Abdolmaleki Sajad Moghadami |
| author_sort | Hossein Bahadoran |
| collection | DOAJ |
| description | Neurulation, as the formation of the basis of the nervous system, is the earliest and crucial stage of embryonic development, affecting the development of other parts of the embryonic body. During neurulation, the neural plate is formed through morphological changes. At the end of this stage, the neural tube is established and the central nervous system could be formed in the future. Although this embryonic process occurs morphologically, the precise study of nervous system evolution can be considered by different gene mutations in rodent embryos. Genetic assessments of embryos can finally cause the accurate discovery of the role of genes in embryo development, the stages of nervous system development, and possible associated diseases. Explanation of new findings in the field of neurulation with emphasis on genetics can be helpful in future embryonic studies, abnormalities, and treatments. Thus, the study of neural plate formation can play an important role in increasing the insight of embryological researchers in this field. In this review article, we aimed to collect basic embryonic data in rodent neurulation to provide important information for more laboratory investigations in this field. |
| first_indexed | 2024-03-10T09:03:26Z |
| format | Article |
| id | doaj.art-8bf7b6e8b1a3483aa1c781db5d8d949f |
| institution | Directory Open Access Journal |
| issn | 2322-3626 |
| language | English |
| last_indexed | 2024-03-10T09:03:26Z |
| publishDate | 2022-08-01 |
| publisher | Negah Institute for Scientific Communication |
| record_format | Article |
| series | Anatomical Sciences Journal |
| spelling | doaj.art-8bf7b6e8b1a3483aa1c781db5d8d949f2023-11-22T06:34:13ZengNegah Institute for Scientific CommunicationAnatomical Sciences Journal2322-36262022-08-011925964Neural Tube Biology With Emphasis on Early Neurulation; A Narrative ReviewHossein Bahadoran0Reza Dadfar1Mohammad Hosein Asadi2Amir Abdolmaleki3Sajad Moghadami4 Department of Anatomy, School of Medicine, Baqiyatallah Medical Science University, Tehran, Iran. Department of Anatomical Sciences, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran. Department of Anatomy, School of Medicine, Baqiyatallah Medical Science University, Tehran, Iran. Department of Anatomy, School of Medicine, Baqiyatallah Medical Science University, Tehran, Iran. Department of Anatomy, School of Medicine, Baqiyatallah Medical Science University, Tehran, Iran. Neurulation, as the formation of the basis of the nervous system, is the earliest and crucial stage of embryonic development, affecting the development of other parts of the embryonic body. During neurulation, the neural plate is formed through morphological changes. At the end of this stage, the neural tube is established and the central nervous system could be formed in the future. Although this embryonic process occurs morphologically, the precise study of nervous system evolution can be considered by different gene mutations in rodent embryos. Genetic assessments of embryos can finally cause the accurate discovery of the role of genes in embryo development, the stages of nervous system development, and possible associated diseases. Explanation of new findings in the field of neurulation with emphasis on genetics can be helpful in future embryonic studies, abnormalities, and treatments. Thus, the study of neural plate formation can play an important role in increasing the insight of embryological researchers in this field. In this review article, we aimed to collect basic embryonic data in rodent neurulation to provide important information for more laboratory investigations in this field.http://anatomyjournal.ir/article-1-572-en.pdfembryologyneurulationrodentcentral nervous system |
| spellingShingle | Hossein Bahadoran Reza Dadfar Mohammad Hosein Asadi Amir Abdolmaleki Sajad Moghadami Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review Anatomical Sciences Journal embryology neurulation rodent central nervous system |
| title | Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review |
| title_full | Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review |
| title_fullStr | Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review |
| title_full_unstemmed | Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review |
| title_short | Neural Tube Biology With Emphasis on Early Neurulation; A Narrative Review |
| title_sort | neural tube biology with emphasis on early neurulation a narrative review |
| topic | embryology neurulation rodent central nervous system |
| url | http://anatomyjournal.ir/article-1-572-en.pdf |
| work_keys_str_mv | AT hosseinbahadoran neuraltubebiologywithemphasisonearlyneurulationanarrativereview AT rezadadfar neuraltubebiologywithemphasisonearlyneurulationanarrativereview AT mohammadhoseinasadi neuraltubebiologywithemphasisonearlyneurulationanarrativereview AT amirabdolmaleki neuraltubebiologywithemphasisonearlyneurulationanarrativereview AT sajadmoghadami neuraltubebiologywithemphasisonearlyneurulationanarrativereview |