Effect of interleukin (IL)-35 on IL-17 expression and production by human CD4+ T cells

Effect of interleukin (IL)-35 on IL-17 expression and production by human CD4+ T cells

Background Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by inhibiting differentiation of Th17 cells. Th17 differe...

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Bibliographic Details
Main Authors:	Kosuke Okada, Takeki Fujimura, Takeshi Kikuchi, Makoto Aino, Yosuke Kamiya, Ario Izawa, Yuki Iwamura, Hisashi Goto, Iichiro Okabe, Eriko Miyake, Yoshiaki Hasegawa, Makio Mogi, Akio Mitani
Format:	Article
Language:	English
Published:	PeerJ Inc. 2017-02-01
Series:	PeerJ
Subjects:	Interleukin-35 Interleukin-17 Periodontitis Th17 Retinoic acid receptor-related orphan receptor
Online Access:	https://peerj.com/articles/2999.pdf

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