The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors
Background: Brain edema induced by radiotherapy is a common complication in patients with brain tumors, for which medical treatment is the treatment of choice. Adjusted-Da-Chai-Ling-Tang, a Chinese herbal formulation, has been confirmed to be protective against the radiation-induced edema. In this s...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
| Series: | Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=1;spage=19;epage=21;aulast=Ju |
| _version_ | 1818512679322517504 |
|---|---|
| author | Da-Tong Ju Hsing-Lung Chao Chen-Yu Lee Shin-Fang Chung Cheng-Ta Hsieh |
| author_facet | Da-Tong Ju Hsing-Lung Chao Chen-Yu Lee Shin-Fang Chung Cheng-Ta Hsieh |
| author_sort | Da-Tong Ju |
| collection | DOAJ |
| description | Background: Brain edema induced by radiotherapy is a common complication in patients with brain tumors, for which medical treatment is the treatment of choice. Adjusted-Da-Chai-Ling-Tang, a Chinese herbal formulation, has been confirmed to be protective against the radiation-induced edema. In this study, we investigated the efficiency of adjusted-Da-Chai-Ling-Tang in radiation-induced brain edema in patients with brain tumors. Materials and Methods: A total of 46 patients with brain tumors treated with radiotherapy alone or combined with surgery were enrolled. These patients were divided into two groups: The experimental group with adjusted-Da-Chai-Ling-Tang and the control group with conventional medical treatment. Clinical data including symptoms and serologic results were collected pretreatment and on the 4 th , 7 th and 10 th day posttreatment. Magnetic resonance imaging of the brain was performed to investigate changes in brain edema. Results: Clinical symptoms including headache, dizziness, nausea/vomiting and fatigue significantly improved in the experimental group (P < 0.05). No difference in serological results was observed. Brain edema was significantly reduced in the experimental group in magnetic resonance imaging (P < 0.05). Conclusion: Adjusted-Da-Chai-Ling-Tang is effective in the treatment of radiation-induced brain edema in patients with brain tumors. No obvious side effects were observed. |
| first_indexed | 2024-12-10T23:50:14Z |
| format | Article |
| id | doaj.art-8bfb2ac2ca704ab58d421e60809f506b |
| institution | Directory Open Access Journal |
| issn | 1011-4564 |
| language | English |
| last_indexed | 2024-12-10T23:50:14Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Sciences |
| spelling | doaj.art-8bfb2ac2ca704ab58d421e60809f506b2022-12-22T01:28:47ZengWolters Kluwer Medknow PublicationsJournal of Medical Sciences1011-45642015-01-01351192110.4103/1011-4564.151285The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumorsDa-Tong JuHsing-Lung ChaoChen-Yu LeeShin-Fang ChungCheng-Ta HsiehBackground: Brain edema induced by radiotherapy is a common complication in patients with brain tumors, for which medical treatment is the treatment of choice. Adjusted-Da-Chai-Ling-Tang, a Chinese herbal formulation, has been confirmed to be protective against the radiation-induced edema. In this study, we investigated the efficiency of adjusted-Da-Chai-Ling-Tang in radiation-induced brain edema in patients with brain tumors. Materials and Methods: A total of 46 patients with brain tumors treated with radiotherapy alone or combined with surgery were enrolled. These patients were divided into two groups: The experimental group with adjusted-Da-Chai-Ling-Tang and the control group with conventional medical treatment. Clinical data including symptoms and serologic results were collected pretreatment and on the 4 th , 7 th and 10 th day posttreatment. Magnetic resonance imaging of the brain was performed to investigate changes in brain edema. Results: Clinical symptoms including headache, dizziness, nausea/vomiting and fatigue significantly improved in the experimental group (P < 0.05). No difference in serological results was observed. Brain edema was significantly reduced in the experimental group in magnetic resonance imaging (P < 0.05). Conclusion: Adjusted-Da-Chai-Ling-Tang is effective in the treatment of radiation-induced brain edema in patients with brain tumors. No obvious side effects were observed.http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=1;spage=19;epage=21;aulast=JuBrain edemaradiotherapybrain tumoradjusted-Da-Chai-Ling-Tangmagnetic resonance images |
| spellingShingle | Da-Tong Ju Hsing-Lung Chao Chen-Yu Lee Shin-Fang Chung Cheng-Ta Hsieh The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors Journal of Medical Sciences Brain edema radiotherapy brain tumor adjusted-Da-Chai-Ling-Tang magnetic resonance images |
| title | The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors |
| title_full | The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors |
| title_fullStr | The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors |
| title_full_unstemmed | The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors |
| title_short | The efficiency of adjusted-da-chai-ling-tang in radiation-induced brain edema in patients with brain tumors |
| title_sort | efficiency of adjusted da chai ling tang in radiation induced brain edema in patients with brain tumors |
| topic | Brain edema radiotherapy brain tumor adjusted-Da-Chai-Ling-Tang magnetic resonance images |
| url | http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=1;spage=19;epage=21;aulast=Ju |
| work_keys_str_mv | AT datongju theefficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT hsinglungchao theefficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT chenyulee theefficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT shinfangchung theefficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT chengtahsieh theefficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT datongju efficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT hsinglungchao efficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT chenyulee efficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT shinfangchung efficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors AT chengtahsieh efficiencyofadjusteddachailingtanginradiationinducedbrainedemainpatientswithbraintumors |