Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis
Abstract Background Lumbar spinal fusion with rigid spinal fixators as one of the high risk factors related to adjacent-segment failure. The purpose of this study is to investigate how the material properties of spinal fixation rods influence the biomechanical behavior at the instrumented and adjace...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-02-01
|
| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-020-3111-1 |
| _version_ | 1811271170361655296 |
|---|---|
| author | Yueh-Ying Hsieh Fon-Yih Tsuang Yi-Jie Kuo Chia-Hsien Chen Chang-Jung Chiang Chun-Li Lin |
| author_facet | Yueh-Ying Hsieh Fon-Yih Tsuang Yi-Jie Kuo Chia-Hsien Chen Chang-Jung Chiang Chun-Li Lin |
| author_sort | Yueh-Ying Hsieh |
| collection | DOAJ |
| description | Abstract Background Lumbar spinal fusion with rigid spinal fixators as one of the high risk factors related to adjacent-segment failure. The purpose of this study is to investigate how the material properties of spinal fixation rods influence the biomechanical behavior at the instrumented and adjacent levels through the use of the finite element method. Methods Five finite element models were constructed in our study to simulate the human spine pre- and post-surgery. For the four post-surgical models, the spines were implanted with rods made of three different materials: (i) titanium rod, (ii) PEEK rod with interbody PEEK cage, (iii) Biodegradable rod with interbody PEEK cage, and (iv) PEEK cage without pedicle screw fixation (no rods). Results Fusion of the lumbar spine using PEEK or biodegradable rods allowed a similar ROM at both the fusion and adjacent levels under all conditions. The models with PEEK and biodegradable rods also showed a similar increase in contact forces at adjacent facet joints, but both were less than the model with a titanium rod. Conclusions Flexible rods or cages with non-instrumented fusion can mitigate the increased contact forces on adjacent facet joints typically found following spinal fixation, and could also reduce the level of stress shielding at the bone graft. |
| first_indexed | 2024-04-12T22:15:21Z |
| format | Article |
| id | doaj.art-8bfd02cc780b4b0f9ea3af67676a501f |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-04-12T22:15:21Z |
| publishDate | 2020-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-8bfd02cc780b4b0f9ea3af67676a501f2022-12-22T03:14:33ZengBMCBMC Musculoskeletal Disorders1471-24742020-02-012111910.1186/s12891-020-3111-1Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysisYueh-Ying Hsieh0Fon-Yih Tsuang1Yi-Jie Kuo2Chia-Hsien Chen3Chang-Jung Chiang4Chun-Li Lin5Department of Biomedical Engineering, National Yang-Ming UniversityDivision of Neurosurgery, Department of Surgery, National Taiwan University HospitalDepartment of Orthopedic Surgery, School of Medicine, College of Medicine, Taipei Medical UniversityDepartment of Orthopedic Surgery, School of Medicine, College of Medicine, Taipei Medical UniversityDepartment of Orthopedics, Shuang Ho Hospital, Taipei Medical UniversityDepartment of Biomedical Engineering, National Yang-Ming UniversityAbstract Background Lumbar spinal fusion with rigid spinal fixators as one of the high risk factors related to adjacent-segment failure. The purpose of this study is to investigate how the material properties of spinal fixation rods influence the biomechanical behavior at the instrumented and adjacent levels through the use of the finite element method. Methods Five finite element models were constructed in our study to simulate the human spine pre- and post-surgery. For the four post-surgical models, the spines were implanted with rods made of three different materials: (i) titanium rod, (ii) PEEK rod with interbody PEEK cage, (iii) Biodegradable rod with interbody PEEK cage, and (iv) PEEK cage without pedicle screw fixation (no rods). Results Fusion of the lumbar spine using PEEK or biodegradable rods allowed a similar ROM at both the fusion and adjacent levels under all conditions. The models with PEEK and biodegradable rods also showed a similar increase in contact forces at adjacent facet joints, but both were less than the model with a titanium rod. Conclusions Flexible rods or cages with non-instrumented fusion can mitigate the increased contact forces on adjacent facet joints typically found following spinal fixation, and could also reduce the level of stress shielding at the bone graft.https://doi.org/10.1186/s12891-020-3111-1Spinal interbody fusionFlexible rodsFinite element analysisBiomechanical study |
| spellingShingle | Yueh-Ying Hsieh Fon-Yih Tsuang Yi-Jie Kuo Chia-Hsien Chen Chang-Jung Chiang Chun-Li Lin Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis BMC Musculoskeletal Disorders Spinal interbody fusion Flexible rods Finite element analysis Biomechanical study |
| title | Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis |
| title_full | Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis |
| title_fullStr | Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis |
| title_full_unstemmed | Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis |
| title_short | Biomechanical analysis of single-level interbody fusion with different internal fixation rod materials: a finite element analysis |
| title_sort | biomechanical analysis of single level interbody fusion with different internal fixation rod materials a finite element analysis |
| topic | Spinal interbody fusion Flexible rods Finite element analysis Biomechanical study |
| url | https://doi.org/10.1186/s12891-020-3111-1 |
| work_keys_str_mv | AT yuehyinghsieh biomechanicalanalysisofsinglelevelinterbodyfusionwithdifferentinternalfixationrodmaterialsafiniteelementanalysis AT fonyihtsuang biomechanicalanalysisofsinglelevelinterbodyfusionwithdifferentinternalfixationrodmaterialsafiniteelementanalysis AT yijiekuo biomechanicalanalysisofsinglelevelinterbodyfusionwithdifferentinternalfixationrodmaterialsafiniteelementanalysis AT chiahsienchen biomechanicalanalysisofsinglelevelinterbodyfusionwithdifferentinternalfixationrodmaterialsafiniteelementanalysis AT changjungchiang biomechanicalanalysisofsinglelevelinterbodyfusionwithdifferentinternalfixationrodmaterialsafiniteelementanalysis AT chunlilin biomechanicalanalysisofsinglelevelinterbodyfusionwithdifferentinternalfixationrodmaterialsafiniteelementanalysis |