Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein
Abstract Background Rhein can significantly delay the progression of chronic nephropathy. However, its mechanism of action has not been adequately elaborated, which hinders its extensive clinical application. In this work, the effects of rhein on models of TGF-β-induced NRK-49F cellular fibrosis and...
Main Authors: | Li Wang, Xixi Yu, Hongju Li, Dahong He, Su Zeng, Zheng Xiang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-12-01
|
Series: | Chinese Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13020-023-00862-1 |
Similar Items
-
A metabolomic approach to elucidate the inhibitory effects of baicalin in pulmonary fibrosis
by: Hong Chang, et al.
Published: (2021-01-01) -
Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in <i>Panax</i> Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics
by: Cuizhu Wang, et al.
Published: (2020-04-01) -
Evaluation of the chronic intoxication of fluoride on human serum metabolome using untargeted metabolomics
by: Muhammad Usman, et al.
Published: (2022-07-01) -
Comparative study on chemical components of Gannan navel orange in different maturity stages based on UPLC-QTOF-MS metabolomics
by: Jinxue Hou, et al.
Published: (2023-12-01) -
Integrated approach on UPLC-QTOF/MS based active plasma component and metabolomics analysis of Gan Mai Da Zao decoction on the treatment of Alzheimer's disease in rats plasma and urine
by: Meirong Cui, et al.
Published: (2022-07-01)