Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder
Background Urinary tract infection is the most common complication in patients with neurogenic bladder, which severely affects the treatment effect and quality of life of patients. Early identification of its related factors and delivery of targeted measures of prevention and intervention are of gre...
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| Format: | Article |
| Language: | zho |
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Chinese General Practice Publishing House Co., Ltd
2023-07-01
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| Series: | Zhongguo quanke yixue |
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| Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220746.pdf |
| _version_ | 1797216644936761344 |
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| author | HE Manlan, YUAN Ping, HE Lei, CHEN Lu |
| author_facet | HE Manlan, YUAN Ping, HE Lei, CHEN Lu |
| author_sort | HE Manlan, YUAN Ping, HE Lei, CHEN Lu |
| collection | DOAJ |
| description | Background Urinary tract infection is the most common complication in patients with neurogenic bladder, which severely affects the treatment effect and quality of life of patients. Early identification of its related factors and delivery of targeted measures of prevention and intervention are of great significance to improve the prognosis of patients. Recent studies on influencing factors of urinary tract infection in neurogenic bladder are increasing but have controversial results, and there is a lack of relevant systematic reviews and support from evidence-based medicine. Objective To systematically assess the risk factors of urinary tract infection in neurogenic bladder. Methods Databases of PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wanfang Data, CQVIP, and SinoMed were searched for literature on risk factors of urinary tract infection in patients with neurogenic bladder from inception to June 2022. The quality of the included literature was assessed using the Newcastle-Ottawa Scale (NOS) . RevMan 5.3 was used for meta-analysis. Results A total of 13 articles with 3 319 cases were included. The NOS score of the articles ranged from 6 to 8. Meta-analysis results showed that advanced age〔OR≥60=2.50, 95%CI (1.83, 3.41) , P<0.000 01; OR≥65=2.13, 95%CI (1.40, 3.25) , P=0.000 4〕, diabetes〔OR=3.17, 95%CI (2.58, 3.89) , P<0.000 01〕, hypoalbuminemia〔OR=2.26, 95%CI (1.67, 3.06) , P<0.000 01〕, number of strokes ≥2〔OR=3.30, 95%CI (1.70, 6.41) , P=0.000 4〕, indwelling catheter〔OR=2.88, 95%CI (2.09, 3.95) , P<0.000 01〕, frequency of intermittent catheterization ≥2 times/week〔OR=2.44, 95%CI (1.62, 3.68) , P<0.000 1〕, frequency of bladder irrigation≥3 times/week〔OR=2.63, 95%CI (1.66, 4.17) , P<0.000 1〕, duration of bladder function training intervention≥2 weeks〔OR=2.75, 95%CI (1.69, 4.46) , P<0.000 1〕, duration of rehabilitation intervention >7 d〔OR=3.03, 95%CI (1.42, 6.48) , P=0.004〕were associated with increased risk of urinary tract infection in neurogenic bladder; Male〔OR=0.78, 95%CI (0.63, 0.96) , P=0.02〕was associated with decreased risk of urinary tract infection in neurogenic bladder. Conclusion Older age, complicated with diabetes, hypoalbuminemia, number of strokes ≥2, indwelling catheter, frequency of intermittent catheterization ≥2 times/week, frequency of bladder irrigation ≥3 times/week, duration of bladder function training intervention ≥2 weeks, and duration of rehabilitation intervention >7 d may be the risk factors for urinary tract infection in neurogenic bladder. To prevent or reduce the risk of urinary tract infection in these patients, clinical workers should identify the aforementioned high-risk factors as early as possible, and provide the patients with interventions targeting the controllable factors. |
| first_indexed | 2024-04-24T11:49:15Z |
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| id | doaj.art-8bff33155a264728a1720834b91ff6eb |
| institution | Directory Open Access Journal |
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| language | zho |
| last_indexed | 2024-04-24T11:49:15Z |
| publishDate | 2023-07-01 |
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| record_format | Article |
| series | Zhongguo quanke yixue |
| spelling | doaj.art-8bff33155a264728a1720834b91ff6eb2024-04-09T08:18:17ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722023-07-0126212659266510.12114/j.issn.1007-9572.2022.0746Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic BladderHE Manlan, YUAN Ping, HE Lei, CHEN Lu01. Department of Neurosurgery, Nanjing Drum Tower Hospital/the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China;2. Drum Tower Clinical Medical College Affiliated to Jiangsu University, Nanjing 210008, China;3. Department of Nursing, Nanjing Drum Tower Hospital/the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, ChinaBackground Urinary tract infection is the most common complication in patients with neurogenic bladder, which severely affects the treatment effect and quality of life of patients. Early identification of its related factors and delivery of targeted measures of prevention and intervention are of great significance to improve the prognosis of patients. Recent studies on influencing factors of urinary tract infection in neurogenic bladder are increasing but have controversial results, and there is a lack of relevant systematic reviews and support from evidence-based medicine. Objective To systematically assess the risk factors of urinary tract infection in neurogenic bladder. Methods Databases of PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wanfang Data, CQVIP, and SinoMed were searched for literature on risk factors of urinary tract infection in patients with neurogenic bladder from inception to June 2022. The quality of the included literature was assessed using the Newcastle-Ottawa Scale (NOS) . RevMan 5.3 was used for meta-analysis. Results A total of 13 articles with 3 319 cases were included. The NOS score of the articles ranged from 6 to 8. Meta-analysis results showed that advanced age〔OR≥60=2.50, 95%CI (1.83, 3.41) , P<0.000 01; OR≥65=2.13, 95%CI (1.40, 3.25) , P=0.000 4〕, diabetes〔OR=3.17, 95%CI (2.58, 3.89) , P<0.000 01〕, hypoalbuminemia〔OR=2.26, 95%CI (1.67, 3.06) , P<0.000 01〕, number of strokes ≥2〔OR=3.30, 95%CI (1.70, 6.41) , P=0.000 4〕, indwelling catheter〔OR=2.88, 95%CI (2.09, 3.95) , P<0.000 01〕, frequency of intermittent catheterization ≥2 times/week〔OR=2.44, 95%CI (1.62, 3.68) , P<0.000 1〕, frequency of bladder irrigation≥3 times/week〔OR=2.63, 95%CI (1.66, 4.17) , P<0.000 1〕, duration of bladder function training intervention≥2 weeks〔OR=2.75, 95%CI (1.69, 4.46) , P<0.000 1〕, duration of rehabilitation intervention >7 d〔OR=3.03, 95%CI (1.42, 6.48) , P=0.004〕were associated with increased risk of urinary tract infection in neurogenic bladder; Male〔OR=0.78, 95%CI (0.63, 0.96) , P=0.02〕was associated with decreased risk of urinary tract infection in neurogenic bladder. Conclusion Older age, complicated with diabetes, hypoalbuminemia, number of strokes ≥2, indwelling catheter, frequency of intermittent catheterization ≥2 times/week, frequency of bladder irrigation ≥3 times/week, duration of bladder function training intervention ≥2 weeks, and duration of rehabilitation intervention >7 d may be the risk factors for urinary tract infection in neurogenic bladder. To prevent or reduce the risk of urinary tract infection in these patients, clinical workers should identify the aforementioned high-risk factors as early as possible, and provide the patients with interventions targeting the controllable factors.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220746.pdfurinary bladder, neurogenic|urinary tract infection|risk factors|newcastle-ottawa scale|cohort studies|case-control studies|meta analysis |
| spellingShingle | HE Manlan, YUAN Ping, HE Lei, CHEN Lu Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder Zhongguo quanke yixue urinary bladder, neurogenic|urinary tract infection|risk factors|newcastle-ottawa scale|cohort studies|case-control studies|meta analysis |
| title | Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder |
| title_full | Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder |
| title_fullStr | Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder |
| title_full_unstemmed | Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder |
| title_short | Meta-analysis of Risk Factors for Urinary Tract Infection in Neurogenic Bladder |
| title_sort | meta analysis of risk factors for urinary tract infection in neurogenic bladder |
| topic | urinary bladder, neurogenic|urinary tract infection|risk factors|newcastle-ottawa scale|cohort studies|case-control studies|meta analysis |
| url | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220746.pdf |
| work_keys_str_mv | AT hemanlanyuanpingheleichenlu metaanalysisofriskfactorsforurinarytractinfectioninneurogenicbladder |