PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY

<span>Abstract Many blood conservation strategies were developed in the past decades to reduce risk of bleeding and the need for blood products among patients undergoing cardiac surgeries. This study was conducted to define the benefit of reinfusion of preoperative collected autologous blood i...

Full description

Bibliographic Details
Main Author: Othman Abdulmajeed
Format: Article
Language:English
Published: university of basrah 2019-06-01
Series:Basrah Journal of Surgery
Online Access:https://bjsrg.uobasrah.edu.iq/article_163859_447f56997479d5a1a94634d5911ff778.pdf
_version_ 1819019920650797056
author Othman Abdulmajeed
author_facet Othman Abdulmajeed
author_sort Othman Abdulmajeed
collection DOAJ
description <span>Abstract Many blood conservation strategies were developed in the past decades to reduce risk of bleeding and the need for blood products among patients undergoing cardiac surgeries. This study was conducted to define the benefit of reinfusion of preoperative collected autologous blood in reduction of the risk of bleeding and the need for blood and blood products in comparison with tranexamic acid. This single centre single-blinded, randomized study was conducted in Erbil cardiac centre during the period from 1st of November 2018 to 30th of April 2019. A total of 150 patients were divided into three groups with 50 patients for each. The 1st group received nothing, the 2nd group received initially infusion of 200mg/hr of tranexamic acid until reaching 1.5gm/hr, and the 3rd group received one pint of preoperative auto-transfused whole blood. Data on risk of bleeding and the need for blood and blood products were collected using special questionnaire prepared for the reason of this study and were analyzed using appropriate statistical tests. Patients receiving autologous blood showed lower chest tube drainage than the other study groups with a p value of </span>
first_indexed 2024-12-21T03:42:59Z
format Article
id doaj.art-8c02bf93716241e58552d0fe65cdc53e
institution Directory Open Access Journal
issn 1683-3589
2409-501X
language English
last_indexed 2024-12-21T03:42:59Z
publishDate 2019-06-01
publisher university of basrah
record_format Article
series Basrah Journal of Surgery
spelling doaj.art-8c02bf93716241e58552d0fe65cdc53e2022-12-21T19:17:10Zenguniversity of basrahBasrah Journal of Surgery1683-35892409-501X2019-06-01251273110.33762/bsurg.2019.163859163859PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERYOthman Abdulmajeed0College of Medicine, Hawler Medical University, Erbil, IRAQ<span>Abstract Many blood conservation strategies were developed in the past decades to reduce risk of bleeding and the need for blood products among patients undergoing cardiac surgeries. This study was conducted to define the benefit of reinfusion of preoperative collected autologous blood in reduction of the risk of bleeding and the need for blood and blood products in comparison with tranexamic acid. This single centre single-blinded, randomized study was conducted in Erbil cardiac centre during the period from 1st of November 2018 to 30th of April 2019. A total of 150 patients were divided into three groups with 50 patients for each. The 1st group received nothing, the 2nd group received initially infusion of 200mg/hr of tranexamic acid until reaching 1.5gm/hr, and the 3rd group received one pint of preoperative auto-transfused whole blood. Data on risk of bleeding and the need for blood and blood products were collected using special questionnaire prepared for the reason of this study and were analyzed using appropriate statistical tests. Patients receiving autologous blood showed lower chest tube drainage than the other study groups with a p value of </span>https://bjsrg.uobasrah.edu.iq/article_163859_447f56997479d5a1a94634d5911ff778.pdf
spellingShingle Othman Abdulmajeed
PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
Basrah Journal of Surgery
title PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
title_full PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
title_fullStr PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
title_full_unstemmed PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
title_short PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
title_sort prophylactic tranexamic acid versus autologous blood transfusion to reduce bleeding in elective coronary bypass graft surgery
url https://bjsrg.uobasrah.edu.iq/article_163859_447f56997479d5a1a94634d5911ff778.pdf
work_keys_str_mv AT othmanabdulmajeed prophylactictranexamicacidversusautologousbloodtransfusiontoreducebleedinginelectivecoronarybypassgraftsurgery