Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review
Human Papillomavirus (HPV) are non enveloped Deoxyribonucleic Acid (DNA) viruses, sized between 50-55 nm, that form two distinct groups to cause epithelial proliferation at cutaneous and mucosal surfaces, which are mostly benign. With more than 100 different HPV types, estimated 30-40 strains affe...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2023-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/18167/61080_CE[Ra1]_F(IS)_PF1(HB_SHU_OM)_PFA(HB_KM)_PN(KM).pdf |
| _version_ | 1797775704778080256 |
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| author | Nidhi Pugalia Adarsh Lata Singh Meenakshi Chandak |
| author_facet | Nidhi Pugalia Adarsh Lata Singh Meenakshi Chandak |
| author_sort | Nidhi Pugalia |
| collection | DOAJ |
| description | Human Papillomavirus (HPV) are non enveloped Deoxyribonucleic Acid (DNA) viruses, sized between 50-55 nm, that form two
distinct groups to cause epithelial proliferation at cutaneous and mucosal surfaces, which are mostly benign. With more than 100
different HPV types, estimated 30-40 strains affect human genital tract. Of which, 16, 18, 31, 33, 35, 39, 45, 51, 52, and 5 are the
oncogenic (high-risk) types associated with cervical, vulvar, vaginal, and anal cancers, and 6, 11, 40, 42, 43, 44, and 54 are non
oncogenic (low-risk) types and are associated with genital warts. HPV 6 and 11 are more commonly associated with genital warts
and are also responsible for approximately 90% of these lesions. Despite a series of modalities available to treat HPV, that range
from topical to immunotherapeutic modalities to surgically destructive procedures, there is no promising, stand-alone modality
which still is a cause of dilemma for Dermatologists while treating warts. The present article reviews all the treatment modalities
commonly applied in practice and also the areas less explored by their level of evidences. |
| first_indexed | 2024-03-12T22:40:26Z |
| format | Article |
| id | doaj.art-8c046b842a1745748590a84d4b1897d1 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-12T22:40:26Z |
| publishDate | 2023-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-8c046b842a1745748590a84d4b1897d12023-07-21T09:51:56ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-07-01177010510.7860/JCDR/2023/61080.18167Treatment Modalities of Cutaneous and Genital Warts: A Narrative ReviewNidhi Pugalia0Adarsh Lata Singh1Meenakshi Chandak2Junior Resident, Department of Dermatology, Datta Meghe Institute of Higher Education and Research, Jawaharlal Nehru Medical College, AVBRH, Sawangi Meghe, Wardha, Maharashtra, India.Professor, Department of Dermatology, Datta Meghe Institute of Higher Education and Research, Jawaharlal Nehru Medical College, AVBRH, Sawangi Meghe, Wardha, Maharashtra, India.Senior Resident, Department of Dermatology, Datta Meghe Institute of Higher Education and Research, Jawaharlal Nehru Medical College, AVBRH, Sawangi Meghe, Wardha, Maharashtra, India.Human Papillomavirus (HPV) are non enveloped Deoxyribonucleic Acid (DNA) viruses, sized between 50-55 nm, that form two distinct groups to cause epithelial proliferation at cutaneous and mucosal surfaces, which are mostly benign. With more than 100 different HPV types, estimated 30-40 strains affect human genital tract. Of which, 16, 18, 31, 33, 35, 39, 45, 51, 52, and 5 are the oncogenic (high-risk) types associated with cervical, vulvar, vaginal, and anal cancers, and 6, 11, 40, 42, 43, 44, and 54 are non oncogenic (low-risk) types and are associated with genital warts. HPV 6 and 11 are more commonly associated with genital warts and are also responsible for approximately 90% of these lesions. Despite a series of modalities available to treat HPV, that range from topical to immunotherapeutic modalities to surgically destructive procedures, there is no promising, stand-alone modality which still is a cause of dilemma for Dermatologists while treating warts. The present article reviews all the treatment modalities commonly applied in practice and also the areas less explored by their level of evidences.https://www.jcdr.net/articles/PDF/18167/61080_CE[Ra1]_F(IS)_PF1(HB_SHU_OM)_PFA(HB_KM)_PN(KM).pdfanogenitalhuman papillomavirusimmunotheraputic modalitiesverruca |
| spellingShingle | Nidhi Pugalia Adarsh Lata Singh Meenakshi Chandak Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review Journal of Clinical and Diagnostic Research anogenital human papillomavirus immunotheraputic modalities verruca |
| title | Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review |
| title_full | Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review |
| title_fullStr | Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review |
| title_full_unstemmed | Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review |
| title_short | Treatment Modalities of Cutaneous and Genital Warts: A Narrative Review |
| title_sort | treatment modalities of cutaneous and genital warts a narrative review |
| topic | anogenital human papillomavirus immunotheraputic modalities verruca |
| url | https://www.jcdr.net/articles/PDF/18167/61080_CE[Ra1]_F(IS)_PF1(HB_SHU_OM)_PFA(HB_KM)_PN(KM).pdf |
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