Case report: Non-response to fluoxetine in a homozygous 5-HTTLPR S-allele carrier of the serotonin transporter gene

Case report: Non-response to fluoxetine in a homozygous 5-HTTLPR S-allele carrier of the serotonin transporter gene

We report the case of a 50-year-old male with major depressive disorder (MDD) to illustrate the challenge of finding effective antidepressant pharmacotherapy and the role that the patient’s genetic makeup may play. Recent treatment attempts before clinic admission included venlafaxine and fluoxetine...

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Bibliographic Details
Main Authors: Céline K. Stäuble, Rebecca Meier, Markus L. Lampert, Thorsten Mikoteit, Martin Hatzinger, Samuel S. Allemann, Kurt E. Hersberger, Henriette E. Meyer zu Schwabedissen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Psychiatry
Subjects:
pharmacogenetics
depression
pharmaceutical care
SLC6A4
5-HTT
ABCB1
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.942268/full

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