Mood disorders in Huntington’s disease: from behavior to cellular and molecular mechanisms

Mood disorders in Huntington’s disease: from behavior to cellular and molecular mechanisms

Huntington’s disease (HD) is a neurodegenerative disorder that is best known for its effect on motor control. Mood disturbances such as depression, anxiety, and irritability also have a high prevalence in patients with HD, and often start before the onset of motor symptoms. Various rodent models of...

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Bibliographic Details
Main Authors: Patrick ePla, Sophie eOrvoen, Frédéric eSaudou, Denis Joseph DAVID, Sandrine eHumbert
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Anxiety
Depression
Neurogenesis
Serotonin
BDNF
Huntingtin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00135/full

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