ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter
Background: New-onset atrial fibrillation (AF) after ablation of typical atrial flutter (AFL) is not rare. This study aimed to investigate the predictive value of electrocardiographic parameters on new-onset AF post-typical AFL ablation.Methods: A total of 158 consecutive patients (79.1% males, mean...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-11-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2021.739350/full |
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| author | Hailei Liu Zhoushan Gu Chao Zhu Mingfang Li Jincheng Jiao Hongwu Chen Gang Yang Weizhu Ju Kai Gu Fengxiang Zhang Lin Yee Chen Di Yang Minglong Chen |
| author_facet | Hailei Liu Zhoushan Gu Chao Zhu Mingfang Li Jincheng Jiao Hongwu Chen Gang Yang Weizhu Ju Kai Gu Fengxiang Zhang Lin Yee Chen Di Yang Minglong Chen |
| author_sort | Hailei Liu |
| collection | DOAJ |
| description | Background: New-onset atrial fibrillation (AF) after ablation of typical atrial flutter (AFL) is not rare. This study aimed to investigate the predictive value of electrocardiographic parameters on new-onset AF post-typical AFL ablation.Methods: A total of 158 consecutive patients (79.1% males, mean age 57.8 ± 14.3 years) with typical AFL were enrolled between January 2012 and August 2017 in this single-center study. Patients with a history of AF before ablation were excluded. ECGs during sinus rhythm (SR) and AFL were collected. The duration of the negative component of flutter wave in lead II (DFNII), proportion of the DFNII of the total circle length of AFL (DFNII%), amplitude of the negative component of flutter wave in lead II (AFNII), duration (DPNV1), and amplitude (APNV1) of negative component of the P wave in lead V1, and P wave duration in lead II (DPII) during sinus rhythm were measured.Results: During a median follow-up of 26.9 ± 11.8 months, 22 cases (13.9%) developed new-onset AF. DFNII was significantly longer in patients with new-onset AF compared to patients without AF (114.7 ± 29.6 ms vs. 82.7 ± 12.8 ms, p < 0.0001). AFNII was significantly lower (0.118 ± 0.034 mV vs. 0.168 ± 0.051 mV, p < 0.0001), DPII (144.21 ± 23.77 ms vs. 111.46 ± 14.19 ms, p < 0.0001), and DPNV1 was significantly longer (81.07 ± 16.87 ms vs. 59.86 ± 14.42 ms, p < 0.0001) in patients with new-onset AF. In the multivariate analysis, DFNII [odds ratio (OR), 1.428; 95% CI, 1.039–1.962; p = 0.028] and DPII (OR, 1.429; 95% CI, 1.046–1.953; p = 0.025) were found to be independently associated with new-onset AF after typical AFL ablation.Conclusion: Parameters representing left atrial activation time under both the SR and AFL were independently associated with new-onset AF post-typical AFL ablation and may be useful in risk prediction, which needs to be confirmed by further prospective studies. |
| first_indexed | 2024-12-20T06:11:10Z |
| format | Article |
| id | doaj.art-8c0cd1c6f9724ed983ec8c408a8b6770 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-20T06:11:10Z |
| publishDate | 2021-11-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-8c0cd1c6f9724ed983ec8c408a8b67702022-12-21T19:50:41ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-11-01810.3389/fcvm.2021.739350739350ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial FlutterHailei Liu0Zhoushan Gu1Chao Zhu2Mingfang Li3Jincheng Jiao4Hongwu Chen5Gang Yang6Weizhu Ju7Kai Gu8Fengxiang Zhang9Lin Yee Chen10Di Yang11Minglong Chen12Division of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, United StatesDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, ChinaBackground: New-onset atrial fibrillation (AF) after ablation of typical atrial flutter (AFL) is not rare. This study aimed to investigate the predictive value of electrocardiographic parameters on new-onset AF post-typical AFL ablation.Methods: A total of 158 consecutive patients (79.1% males, mean age 57.8 ± 14.3 years) with typical AFL were enrolled between January 2012 and August 2017 in this single-center study. Patients with a history of AF before ablation were excluded. ECGs during sinus rhythm (SR) and AFL were collected. The duration of the negative component of flutter wave in lead II (DFNII), proportion of the DFNII of the total circle length of AFL (DFNII%), amplitude of the negative component of flutter wave in lead II (AFNII), duration (DPNV1), and amplitude (APNV1) of negative component of the P wave in lead V1, and P wave duration in lead II (DPII) during sinus rhythm were measured.Results: During a median follow-up of 26.9 ± 11.8 months, 22 cases (13.9%) developed new-onset AF. DFNII was significantly longer in patients with new-onset AF compared to patients without AF (114.7 ± 29.6 ms vs. 82.7 ± 12.8 ms, p < 0.0001). AFNII was significantly lower (0.118 ± 0.034 mV vs. 0.168 ± 0.051 mV, p < 0.0001), DPII (144.21 ± 23.77 ms vs. 111.46 ± 14.19 ms, p < 0.0001), and DPNV1 was significantly longer (81.07 ± 16.87 ms vs. 59.86 ± 14.42 ms, p < 0.0001) in patients with new-onset AF. In the multivariate analysis, DFNII [odds ratio (OR), 1.428; 95% CI, 1.039–1.962; p = 0.028] and DPII (OR, 1.429; 95% CI, 1.046–1.953; p = 0.025) were found to be independently associated with new-onset AF after typical AFL ablation.Conclusion: Parameters representing left atrial activation time under both the SR and AFL were independently associated with new-onset AF post-typical AFL ablation and may be useful in risk prediction, which needs to be confirmed by further prospective studies.https://www.frontiersin.org/articles/10.3389/fcvm.2021.739350/fulltypical AFLnew-onset AFECG componentspredictingablation |
| spellingShingle | Hailei Liu Zhoushan Gu Chao Zhu Mingfang Li Jincheng Jiao Hongwu Chen Gang Yang Weizhu Ju Kai Gu Fengxiang Zhang Lin Yee Chen Di Yang Minglong Chen ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter Frontiers in Cardiovascular Medicine typical AFL new-onset AF ECG components predicting ablation |
| title | ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter |
| title_full | ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter |
| title_fullStr | ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter |
| title_full_unstemmed | ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter |
| title_short | ECG Predictors for New-Onset Atrial Fibrillation Within a Year After Radiofrequency Ablation of Counterclockwise-Rotating Atrial Flutter |
| title_sort | ecg predictors for new onset atrial fibrillation within a year after radiofrequency ablation of counterclockwise rotating atrial flutter |
| topic | typical AFL new-onset AF ECG components predicting ablation |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2021.739350/full |
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