Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19
Abstract Background Coronavirus disease 2019 (COVID-19) pandemic is considered a global health crisis. The data related to chronic obstructive pulmonary disease (COPD) patients with COVID-19 are incomplete, especially the findings of the chest computed tomography (CT). The aim of the current study w...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-023-01336-8 |
| _version_ | 1797453487414444032 |
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| author | Yalda Alipour Khabir Sevda Alipour Khabir Hassan Anari Bahman Mohammadzadeh Saeed Hoseininia Mohammad Reza Aslani |
| author_facet | Yalda Alipour Khabir Sevda Alipour Khabir Hassan Anari Bahman Mohammadzadeh Saeed Hoseininia Mohammad Reza Aslani |
| author_sort | Yalda Alipour Khabir |
| collection | DOAJ |
| description | Abstract Background Coronavirus disease 2019 (COVID-19) pandemic is considered a global health crisis. The data related to chronic obstructive pulmonary disease (COPD) patients with COVID-19 are incomplete, especially the findings of the chest computed tomography (CT). The aim of the current study was to investigate the severity of the disease of COVID-19 in patients with COPD based on CT severity score and to evaluate its predictive power in the mortality of patients. Methods In a retrospective study, demographic, clinical, and CT scan findings of COPD patients with COVID-19 were extracted from March 2020 to February 2022. CT severity score was determined based on the extent and nature of involvement of lungs in CT scan findings. By performing receiver operating characteristics (ROC) and Kaplan–Meier survival analysis were determined the disease severity and survival probability. Results The most frequent radiological findings in chest CT scan included ground glass opacities (89.3%), consolidations (51.8%), crazy-paving pattern (46.4%), and septal thickening (35.7%). The mean CT severity score of deceased patients (34.61 ± 18.73) was significantly higher than recovered patients (16.71 ± 14.01, p < 0.001). Based on the ROC and Kaplan–Meier survival curves, it was revealed that CT severity score was a valuable criteria in the diagnosis of mortality in COPD patients with COVID-19. Conclusion The findings of this study revealed that the CT severity scoring in COPD patients with COVID-19 was valuable in identifying poor prognosis, although further studies are needed. |
| first_indexed | 2024-03-09T15:23:32Z |
| format | Article |
| id | doaj.art-8c0e1b00cc764878865b045a5e619a50 |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-03-09T15:23:32Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-8c0e1b00cc764878865b045a5e619a502023-11-26T12:41:50ZengBMCEuropean Journal of Medical Research2047-783X2023-09-012811810.1186/s40001-023-01336-8Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19Yalda Alipour Khabir0Sevda Alipour Khabir1Hassan Anari2Bahman Mohammadzadeh3Saeed Hoseininia4Mohammad Reza Aslani5Students Research Committee, School of Medicine, Ardabil University of Medical SciencesStudents Research Committee, School of Medicine, Ardabil University of Medical SciencesDepartment of Radiology, Faculty of Medicine, Ardabil University of Medical SciencesDepartment of Radiology, Faculty of Medicine, Ardabil University of Medical SciencesLung Diseases Research Center, Ardabil University of Medical SciencesLung Diseases Research Center, Ardabil University of Medical SciencesAbstract Background Coronavirus disease 2019 (COVID-19) pandemic is considered a global health crisis. The data related to chronic obstructive pulmonary disease (COPD) patients with COVID-19 are incomplete, especially the findings of the chest computed tomography (CT). The aim of the current study was to investigate the severity of the disease of COVID-19 in patients with COPD based on CT severity score and to evaluate its predictive power in the mortality of patients. Methods In a retrospective study, demographic, clinical, and CT scan findings of COPD patients with COVID-19 were extracted from March 2020 to February 2022. CT severity score was determined based on the extent and nature of involvement of lungs in CT scan findings. By performing receiver operating characteristics (ROC) and Kaplan–Meier survival analysis were determined the disease severity and survival probability. Results The most frequent radiological findings in chest CT scan included ground glass opacities (89.3%), consolidations (51.8%), crazy-paving pattern (46.4%), and septal thickening (35.7%). The mean CT severity score of deceased patients (34.61 ± 18.73) was significantly higher than recovered patients (16.71 ± 14.01, p < 0.001). Based on the ROC and Kaplan–Meier survival curves, it was revealed that CT severity score was a valuable criteria in the diagnosis of mortality in COPD patients with COVID-19. Conclusion The findings of this study revealed that the CT severity scoring in COPD patients with COVID-19 was valuable in identifying poor prognosis, although further studies are needed.https://doi.org/10.1186/s40001-023-01336-8COVID-19Chronic obstructive pulmonary diseaseComputed tomography |
| spellingShingle | Yalda Alipour Khabir Sevda Alipour Khabir Hassan Anari Bahman Mohammadzadeh Saeed Hoseininia Mohammad Reza Aslani Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19 European Journal of Medical Research COVID-19 Chronic obstructive pulmonary disease Computed tomography |
| title | Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19 |
| title_full | Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19 |
| title_fullStr | Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19 |
| title_full_unstemmed | Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19 |
| title_short | Chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co-infected with COVID-19 |
| title_sort | chest computed tomography severity score is a reliable predictor of mortality in patients with chronic obstructive pulmonary disease co infected with covid 19 |
| topic | COVID-19 Chronic obstructive pulmonary disease Computed tomography |
| url | https://doi.org/10.1186/s40001-023-01336-8 |
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