Multimodality imaging review of focal renal lesions

Abstract Background Focal lesions of the kidney comprise a spectrum of entities that can be broadly classified as malignant tumors, benign tumors, and non-neoplastic lesions. Malignant tumors include renal cell carcinoma subtypes, urothelial carcinoma, lymphoma, post-transplant lymphoproliferative d...

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Main Authors: Jonathan Lyske, Rishi Philip Mathew, Christopher Hutchinson, Vimal Patel, Gavin Low
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:https://doi.org/10.1186/s43055-020-00391-z
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author Jonathan Lyske
Rishi Philip Mathew
Christopher Hutchinson
Vimal Patel
Gavin Low
author_facet Jonathan Lyske
Rishi Philip Mathew
Christopher Hutchinson
Vimal Patel
Gavin Low
author_sort Jonathan Lyske
collection DOAJ
description Abstract Background Focal lesions of the kidney comprise a spectrum of entities that can be broadly classified as malignant tumors, benign tumors, and non-neoplastic lesions. Malignant tumors include renal cell carcinoma subtypes, urothelial carcinoma, lymphoma, post-transplant lymphoproliferative disease, metastases to the kidney, and rare malignant lesions. Benign tumors include angiomyolipoma (fat-rich and fat-poor) and oncocytoma. Non-neoplastic lesions include infective, inflammatory, and vascular entities. Anatomical variants can also mimic focal masses. Main body of the abstract A range of imaging modalities are available to facilitate characterization; ultrasound (US), contrast-enhanced ultrasound (CEUS), computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET), each with their own strengths and limitations. Renal lesions are being detected with increasing frequency due to escalating imaging volumes. Accurate diagnosis is central to guiding clinical management and determining prognosis. Certain lesions require intervention, whereas others may be managed conservatively or deemed clinically insignificant. Challenging cases often benefit from a multimodality imaging approach combining the morphology, enhancement and metabolic features. Short conclusion Knowledge of the relevant clinical details and key imaging features is crucial for accurate characterization and differentiation of renal lesions.
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spelling doaj.art-8c0e355f6e044917928c8f10a9ea76e52022-12-21T23:19:38ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622021-01-0152111910.1186/s43055-020-00391-zMultimodality imaging review of focal renal lesionsJonathan Lyske0Rishi Philip Mathew1Christopher Hutchinson2Vimal Patel3Gavin Low4Department of Radiology & Diagnostic Imaging, Faculty of Medicine and Dentistry, University of AlbertaDepartment of Radiology, Rajagiri HospitalDepartment of Radiology & Diagnostic Imaging, Faculty of Medicine and Dentistry, University of AlbertaDepartment of Radiology & Diagnostic Imaging, Faculty of Medicine and Dentistry, University of AlbertaDepartment of Radiology & Diagnostic Imaging, Faculty of Medicine and Dentistry, University of AlbertaAbstract Background Focal lesions of the kidney comprise a spectrum of entities that can be broadly classified as malignant tumors, benign tumors, and non-neoplastic lesions. Malignant tumors include renal cell carcinoma subtypes, urothelial carcinoma, lymphoma, post-transplant lymphoproliferative disease, metastases to the kidney, and rare malignant lesions. Benign tumors include angiomyolipoma (fat-rich and fat-poor) and oncocytoma. Non-neoplastic lesions include infective, inflammatory, and vascular entities. Anatomical variants can also mimic focal masses. Main body of the abstract A range of imaging modalities are available to facilitate characterization; ultrasound (US), contrast-enhanced ultrasound (CEUS), computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET), each with their own strengths and limitations. Renal lesions are being detected with increasing frequency due to escalating imaging volumes. Accurate diagnosis is central to guiding clinical management and determining prognosis. Certain lesions require intervention, whereas others may be managed conservatively or deemed clinically insignificant. Challenging cases often benefit from a multimodality imaging approach combining the morphology, enhancement and metabolic features. Short conclusion Knowledge of the relevant clinical details and key imaging features is crucial for accurate characterization and differentiation of renal lesions.https://doi.org/10.1186/s43055-020-00391-zRenal cell carcinomaLymphomaPost-transplant lymphoproliferative diseaseRenal metastasesAngiomyolipomaOncocytoma
spellingShingle Jonathan Lyske
Rishi Philip Mathew
Christopher Hutchinson
Vimal Patel
Gavin Low
Multimodality imaging review of focal renal lesions
The Egyptian Journal of Radiology and Nuclear Medicine
Renal cell carcinoma
Lymphoma
Post-transplant lymphoproliferative disease
Renal metastases
Angiomyolipoma
Oncocytoma
title Multimodality imaging review of focal renal lesions
title_full Multimodality imaging review of focal renal lesions
title_fullStr Multimodality imaging review of focal renal lesions
title_full_unstemmed Multimodality imaging review of focal renal lesions
title_short Multimodality imaging review of focal renal lesions
title_sort multimodality imaging review of focal renal lesions
topic Renal cell carcinoma
Lymphoma
Post-transplant lymphoproliferative disease
Renal metastases
Angiomyolipoma
Oncocytoma
url https://doi.org/10.1186/s43055-020-00391-z
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AT rishiphilipmathew multimodalityimagingreviewoffocalrenallesions
AT christopherhutchinson multimodalityimagingreviewoffocalrenallesions
AT vimalpatel multimodalityimagingreviewoffocalrenallesions
AT gavinlow multimodalityimagingreviewoffocalrenallesions