Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic
The explosive rise in angioinvasive mucormycosis (MM) in India and other parts of the world has been described as the “epidemic following the COVID-19 pandemic,” with the majority being rhino-orbital-cerebral MM. We report a case series of five COVID-19-associated pulmonary MM (CAPM) with an aggress...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Lung India |
| Subjects: | |
| Online Access: | http://www.lungindia.com/article.asp?issn=0970-2113;year=2022;volume=39;issue=2;spage=187;epage=190;aulast=Mehta |
| _version_ | 1818199581735780352 |
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| author | Ravindra M Mehta Sameer Bansal Hariprasad Kalpakkam |
| author_facet | Ravindra M Mehta Sameer Bansal Hariprasad Kalpakkam |
| author_sort | Ravindra M Mehta |
| collection | DOAJ |
| description | The explosive rise in angioinvasive mucormycosis (MM) in India and other parts of the world has been described as the “epidemic following the COVID-19 pandemic,” with the majority being rhino-orbital-cerebral MM. We report a case series of five COVID-19-associated pulmonary MM (CAPM) with an aggressive clinical course. Clinical and radiological clues were limited, and the initial suspicion of CAPM was the morphological appearance on bronchoscopy, which led to the diagnosis. Histopathology was consistently positive in all cases, while other microbiological and molecular tests had varying sensitivity. Most patients had a fulminant and fatal course. Also noted was dual fungal infection in 3/5 cases with coexisting multidrug resistant bacterial infection in all cases. CAPM is the hidden part of the COVID-MM epidemic and warrants a high degree of suspicion with early diagnosis and treatment. |
| first_indexed | 2024-12-12T02:24:03Z |
| format | Article |
| id | doaj.art-8c10d44f710641dc9221c4877bc471d2 |
| institution | Directory Open Access Journal |
| issn | 0970-2113 0974-598X |
| language | English |
| last_indexed | 2024-12-12T02:24:03Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Lung India |
| spelling | doaj.art-8c10d44f710641dc9221c4877bc471d22022-12-22T00:41:37ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2022-01-0139218719010.4103/lungindia.lungindia_435_21Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemicRavindra M MehtaSameer BansalHariprasad KalpakkamThe explosive rise in angioinvasive mucormycosis (MM) in India and other parts of the world has been described as the “epidemic following the COVID-19 pandemic,” with the majority being rhino-orbital-cerebral MM. We report a case series of five COVID-19-associated pulmonary MM (CAPM) with an aggressive clinical course. Clinical and radiological clues were limited, and the initial suspicion of CAPM was the morphological appearance on bronchoscopy, which led to the diagnosis. Histopathology was consistently positive in all cases, while other microbiological and molecular tests had varying sensitivity. Most patients had a fulminant and fatal course. Also noted was dual fungal infection in 3/5 cases with coexisting multidrug resistant bacterial infection in all cases. CAPM is the hidden part of the COVID-MM epidemic and warrants a high degree of suspicion with early diagnosis and treatment.http://www.lungindia.com/article.asp?issn=0970-2113;year=2022;volume=39;issue=2;spage=187;epage=190;aulast=Mehtabronchoscopycovidcovid fungal infectioncovid-19-associated pulmonary mucormycosismucormycosispulmonary mucormycosis |
| spellingShingle | Ravindra M Mehta Sameer Bansal Hariprasad Kalpakkam Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic Lung India bronchoscopy covid covid fungal infection covid-19-associated pulmonary mucormycosis mucormycosis pulmonary mucormycosis |
| title | Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic |
| title_full | Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic |
| title_fullStr | Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic |
| title_full_unstemmed | Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic |
| title_short | Critical COVID-19-associated pulmonary mucormycosis: The underreported life-threatening spectrum of the mucormycosis epidemic |
| title_sort | critical covid 19 associated pulmonary mucormycosis the underreported life threatening spectrum of the mucormycosis epidemic |
| topic | bronchoscopy covid covid fungal infection covid-19-associated pulmonary mucormycosis mucormycosis pulmonary mucormycosis |
| url | http://www.lungindia.com/article.asp?issn=0970-2113;year=2022;volume=39;issue=2;spage=187;epage=190;aulast=Mehta |
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