White Adipose Tissue Depots Respond to Chronic Beta-3 Adrenergic Receptor Activation in a Sexually Dimorphic and Depot Divergent Manner

White Adipose Tissue Depots Respond to Chronic Beta-3 Adrenergic Receptor Activation in a Sexually Dimorphic and Depot Divergent Manner

Beta-3 adrenergic receptor activation via exercise or CL316,243 (CL) induces white adipose tissue (WAT) browning, improves glucose tolerance, and reduces visceral adiposity. Our aim was to determine if sex or adipose tissue depot differences exist in response to CL. Daily CL injections were administ...

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Bibliographic Details
Main Authors: Eric D. Queathem, Rebecca J. Welly, Laura M. Clart, Candace C. Rowles, Hunter Timmons, Maggie Fitzgerald, Peggy A. Eichen, Dennis B. Lubahn, Victoria J. Vieira-Potter
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
adrenergic activity
browning
insulin resistance
sex differences
UCP1
estrogen signaling
Online Access:https://www.mdpi.com/2073-4409/10/12/3453

Internet

https://www.mdpi.com/2073-4409/10/12/3453

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