Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism
The deposition of amyloid β peptide (Aβ) is one of the main pathological features of AD. The much-talked sensory gamma entrainment may be a new treatment for Aβ load. Here we reviewed the generation and clearance pathways of Aβ, aberrant gamma oscillation in AD, and the therapeutic effect of sensory...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Brain Research Bulletin |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923023001752 |
| _version_ | 1797677687071834112 |
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| author | Jiaying Hu Leyan Zheng Ziyu Guan Kexin Zhong Fankai Huang Qiankai Huang Jing Yang Weiyun Li Shanshan Li |
| author_facet | Jiaying Hu Leyan Zheng Ziyu Guan Kexin Zhong Fankai Huang Qiankai Huang Jing Yang Weiyun Li Shanshan Li |
| author_sort | Jiaying Hu |
| collection | DOAJ |
| description | The deposition of amyloid β peptide (Aβ) is one of the main pathological features of AD. The much-talked sensory gamma entrainment may be a new treatment for Aβ load. Here we reviewed the generation and clearance pathways of Aβ, aberrant gamma oscillation in AD, and the therapeutic effect of sensory gamma entrainment on AD. In addition, we discuss these results based on stimulus parameters and possible potential mechanisms. This provides the support for sensory gamma entrainment targeting Aβ to improve AD. |
| first_indexed | 2024-03-11T22:48:52Z |
| format | Article |
| id | doaj.art-8c1444f38ab146898cf801df65cbb2f0 |
| institution | Directory Open Access Journal |
| issn | 1873-2747 |
| language | English |
| last_indexed | 2024-03-11T22:48:52Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Research Bulletin |
| spelling | doaj.art-8c1444f38ab146898cf801df65cbb2f02023-09-22T04:37:58ZengElsevierBrain Research Bulletin1873-27472023-10-01202110750Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanismJiaying Hu0Leyan Zheng1Ziyu Guan2Kexin Zhong3Fankai Huang4Qiankai Huang5Jing Yang6Weiyun Li7Shanshan Li8Department of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, ChinaDepartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China; Corresponding author at: Department of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China.The deposition of amyloid β peptide (Aβ) is one of the main pathological features of AD. The much-talked sensory gamma entrainment may be a new treatment for Aβ load. Here we reviewed the generation and clearance pathways of Aβ, aberrant gamma oscillation in AD, and the therapeutic effect of sensory gamma entrainment on AD. In addition, we discuss these results based on stimulus parameters and possible potential mechanisms. This provides the support for sensory gamma entrainment targeting Aβ to improve AD.http://www.sciencedirect.com/science/article/pii/S0361923023001752Alzheimer's diseaseSensory gamma entrainmentAmyloid beta peptideAmyloid precursor protein |
| spellingShingle | Jiaying Hu Leyan Zheng Ziyu Guan Kexin Zhong Fankai Huang Qiankai Huang Jing Yang Weiyun Li Shanshan Li Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism Brain Research Bulletin Alzheimer's disease Sensory gamma entrainment Amyloid beta peptide Amyloid precursor protein |
| title | Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism |
| title_full | Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism |
| title_fullStr | Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism |
| title_full_unstemmed | Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism |
| title_short | Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism |
| title_sort | sensory gamma entrainment impact on amyloid protein and therapeutic mechanism |
| topic | Alzheimer's disease Sensory gamma entrainment Amyloid beta peptide Amyloid precursor protein |
| url | http://www.sciencedirect.com/science/article/pii/S0361923023001752 |
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