Preparation of drug-loaded iridium oxidenanocomposites and its application in synergetic sonodynamic/chemotherapeutic therapy against cancer

Preparation of drug-loaded iridium oxidenanocomposites and its application in synergetic sonodynamic/chemotherapeutic therapy against cancer

Objective To prepare iridium oxide (IrOX) as a nano-sonosensitizer to load chemotherapy drug doxorubicin (DOX) in order to obtain nanocomposites IrOX@DOX with dual response of pH/ultrasound (US) irradiation, and to verify its efficacy in sonodynamic therapy (SDT)-chemotherapy for tumor treatment. Me...

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Bibliographic Details
Main Authors: ZOU Weijuan, HAO Junnian, WU Jianrong, ZHENG Yuanyi
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-11-01
Series:Di-san junyi daxue xuebao
Subjects:
iridium oxide
sonodynamic therapy
chemotherapy
synergistic therapy
tumor
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202105108.htm

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