Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery
Aims and Objectives: We studied the usefulness of regional cerebral oxygen saturation (rSO 2 ) monitoring during cardiopulmonary bypass (CPB) and evaluated effects of cerebral oxygen desaturation on the postoperative neurological outcome. Materials and Methods: 100 patients were randomly allocated t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Annals of Cardiac Anaesthesia |
| Subjects: | |
| Online Access: | http://www.annals.in/article.asp?issn=0971-9784;year=2013;volume=16;issue=2;spage=102;epage=106;aulast=Mohandas |
| _version_ | 1818253917618700288 |
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| author | B S Mohandas A M Jagadeesh S B Vikram |
| author_facet | B S Mohandas A M Jagadeesh S B Vikram |
| author_sort | B S Mohandas |
| collection | DOAJ |
| description | Aims and Objectives: We studied the usefulness of regional cerebral oxygen saturation (rSO 2 ) monitoring during cardiopulmonary bypass (CPB) and evaluated effects of cerebral oxygen desaturation on the postoperative neurological outcome. Materials and Methods: 100 patients were randomly allocated to either control or intervention group. In the control group rSO 2 was recorded continuously, but the attending anesthesiologist was blinded. In the intervention group specific interventions were initiated in case of cerebral desaturation. Neurocognitive testing was done using a simplified antisaccadic eye movement test (ASEM) and mini-mental state examination (MMSE). Data was analyzed using Chi-square test, and unpaired t-test. Results: In both the groups rSO 2 declined during CPB. The decrease in rSO 2 was significant ( P < 0.001) in the control group compared to the intervention group. In the intervention group the rSO 2 mainly responded to an increase in mean arterial pressure. The area under the curve below threshold rSO 2 was significantly more ( P < 0.0001) in the control group compared to intervention group and a significant decrease in the MMSE and ASEM scores occurred in control group at one week and three months postoperatively. Conclusions: Monitoring of rSO 2 during CPB can significantly decrease the incidence of postoperative neurocognitive decline. |
| first_indexed | 2024-12-12T16:47:41Z |
| format | Article |
| id | doaj.art-8c19e7f79ddc41209e57fc1de686ff82 |
| institution | Directory Open Access Journal |
| issn | 0971-9784 |
| language | English |
| last_indexed | 2024-12-12T16:47:41Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Cardiac Anaesthesia |
| spelling | doaj.art-8c19e7f79ddc41209e57fc1de686ff822022-12-22T00:18:26ZengWolters Kluwer Medknow PublicationsAnnals of Cardiac Anaesthesia0971-97842013-01-0116210210610.4103/0971-9784.109740Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgeryB S MohandasA M JagadeeshS B VikramAims and Objectives: We studied the usefulness of regional cerebral oxygen saturation (rSO 2 ) monitoring during cardiopulmonary bypass (CPB) and evaluated effects of cerebral oxygen desaturation on the postoperative neurological outcome. Materials and Methods: 100 patients were randomly allocated to either control or intervention group. In the control group rSO 2 was recorded continuously, but the attending anesthesiologist was blinded. In the intervention group specific interventions were initiated in case of cerebral desaturation. Neurocognitive testing was done using a simplified antisaccadic eye movement test (ASEM) and mini-mental state examination (MMSE). Data was analyzed using Chi-square test, and unpaired t-test. Results: In both the groups rSO 2 declined during CPB. The decrease in rSO 2 was significant ( P < 0.001) in the control group compared to the intervention group. In the intervention group the rSO 2 mainly responded to an increase in mean arterial pressure. The area under the curve below threshold rSO 2 was significantly more ( P < 0.0001) in the control group compared to intervention group and a significant decrease in the MMSE and ASEM scores occurred in control group at one week and three months postoperatively. Conclusions: Monitoring of rSO 2 during CPB can significantly decrease the incidence of postoperative neurocognitive decline.http://www.annals.in/article.asp?issn=0971-9784;year=2013;volume=16;issue=2;spage=102;epage=106;aulast=MohandasCardiopulmonary bypassCerebral oximetryCognitive dysfunctionMini-mental state examinationAntisaccadic eye movement test |
| spellingShingle | B S Mohandas A M Jagadeesh S B Vikram Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery Annals of Cardiac Anaesthesia Cardiopulmonary bypass Cerebral oximetry Cognitive dysfunction Mini-mental state examination Antisaccadic eye movement test |
| title | Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery |
| title_full | Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery |
| title_fullStr | Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery |
| title_full_unstemmed | Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery |
| title_short | Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery |
| title_sort | impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery |
| topic | Cardiopulmonary bypass Cerebral oximetry Cognitive dysfunction Mini-mental state examination Antisaccadic eye movement test |
| url | http://www.annals.in/article.asp?issn=0971-9784;year=2013;volume=16;issue=2;spage=102;epage=106;aulast=Mohandas |
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