Heterologous expression, purification and biochemical characterization of a glutamate racemase (MurI) from Streptococcus mutans UA159

Background Glutamate racemase (MurI) is a cofactor-independent enzyme that is essential to the bacterial peptidoglycan biosynthesis pathway and has therefore been considered an attractive target for the development of antimicrobial drugs. While in our previous study the essentiality of the murI gene...

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Bibliografiske detaljer
Main Authors: Xiangzhu Wang, Chanchan Chen, Ting Shen, Jiangying Zhang
Format: Article
Sprog:English
Udgivet: PeerJ Inc. 2019-12-01
Serier:PeerJ
Fag:
Online adgang:https://peerj.com/articles/8300.pdf