Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation
Abstract Graft-versus-leukemia (GvL) reactions are responsible for the effectiveness of allogeneic hematopoietic cell transplantation as a treatment modality for myeloid neoplasia, whereby donor T- effector cells recognize leukemia neoantigens. However, a substantial fraction of patients experiences...
Main Authors: | Simona Pagliuca, Carmelo Gurnari, Colin Hercus, Sébastien Hergalant, Sanghee Hong, Adele Dhuyser, Maud D’Aveni, Alice Aarnink, Marie Thérèse Rubio, Pierre Feugier, Francesca Ferraro, Hetty E. Carraway, Ronald Sobecks, Betty K. Hamilton, Navneet S. Majhail, Valeria Visconte, Jaroslaw P. Maciejewski |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-38113-4 |
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