A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses.

Humans express seven human APOBEC3 proteins, which can inhibit viruses and endogenous retroelements through cytidine deaminase activity. The seven paralogs differ in the potency of their antiviral effects, as well as in their antiviral targets. One APOBEC3, APOBEC3C, is exceptional as it has been fo...

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Main Authors: Cristina J Wittkopp, Madison B Adolph, Lily I Wu, Linda Chelico, Michael Emerman
格式: Article
語言:English
出版: Public Library of Science (PLoS) 2016-10-01
叢編:PLoS Pathogens
在線閱讀:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005865&type=printable