Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis

Abstract Background This meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery. Methods A systematic search was performed in PubMed, Embase, and the Cochrane Library databa...

Full description

Bibliographic Details
Main Authors: Cong Wang, Yiwen Zhang, Hao Qu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-019-1488-z
_version_ 1828138352923115520
author Cong Wang
Yiwen Zhang
Hao Qu
author_facet Cong Wang
Yiwen Zhang
Hao Qu
author_sort Cong Wang
collection DOAJ
description Abstract Background This meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery. Methods A systematic search was performed in PubMed, Embase, and the Cochrane Library databases. The outcome measures included deep surgical site infection (SSI), superficial SSI; wound dehiscence and length of hospital stay. Cochrane collaboration’s tool and the Newcastle–Ottawa Scale (NOS) were used to evaluate literature qualities. Meta-analysis was performed using RevMan 5.3 software. Results A total of 6 studies including 2 randomized controlled trials (RCTs) and 4 cohort studies met our inclusion criteria. NPWT resulted in a significantly lower incidence of deep SSI, superficial SSI, and wound dehiscence than conventional wound dressings. However, no statistically significant difference was found in the length of hospital stay. Conclusions NPWT appeared to be an efficient alternative to help prevent SSIs and wound dehiscence on closed incisions in orthopedic trauma surgery. Rational use of NWPT should be based on the presence of patient’s condition and risk factors.
first_indexed 2024-04-11T18:34:24Z
format Article
id doaj.art-8c229e9b1fc946f496e0d4de6b68ba64
institution Directory Open Access Journal
issn 1749-799X
language English
last_indexed 2024-04-11T18:34:24Z
publishDate 2019-12-01
publisher BMC
record_format Article
series Journal of Orthopaedic Surgery and Research
spelling doaj.art-8c229e9b1fc946f496e0d4de6b68ba642022-12-22T04:09:19ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2019-12-011411710.1186/s13018-019-1488-zNegative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysisCong Wang0Yiwen Zhang1Hao Qu2Department of Orthopaedic Surgery, The Second Affiliated Hospital, Zhejiang University School of MedicineOperating Room, The Second Affiliated Hospital, Zhejiang University School of MedicineDepartment of Orthopaedic Surgery, The Second Affiliated Hospital, Zhejiang University School of MedicineAbstract Background This meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery. Methods A systematic search was performed in PubMed, Embase, and the Cochrane Library databases. The outcome measures included deep surgical site infection (SSI), superficial SSI; wound dehiscence and length of hospital stay. Cochrane collaboration’s tool and the Newcastle–Ottawa Scale (NOS) were used to evaluate literature qualities. Meta-analysis was performed using RevMan 5.3 software. Results A total of 6 studies including 2 randomized controlled trials (RCTs) and 4 cohort studies met our inclusion criteria. NPWT resulted in a significantly lower incidence of deep SSI, superficial SSI, and wound dehiscence than conventional wound dressings. However, no statistically significant difference was found in the length of hospital stay. Conclusions NPWT appeared to be an efficient alternative to help prevent SSIs and wound dehiscence on closed incisions in orthopedic trauma surgery. Rational use of NWPT should be based on the presence of patient’s condition and risk factors.https://doi.org/10.1186/s13018-019-1488-zNegative pressure wound therapyConventional wound dressingsSurgical site infectionClosed incisionsOrthopaedic traumaMeta-analysis
spellingShingle Cong Wang
Yiwen Zhang
Hao Qu
Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis
Journal of Orthopaedic Surgery and Research
Negative pressure wound therapy
Conventional wound dressings
Surgical site infection
Closed incisions
Orthopaedic trauma
Meta-analysis
title Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis
title_full Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis
title_fullStr Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis
title_full_unstemmed Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis
title_short Negative pressure wound therapy for closed incisions in orthopedic trauma surgery: a meta-analysis
title_sort negative pressure wound therapy for closed incisions in orthopedic trauma surgery a meta analysis
topic Negative pressure wound therapy
Conventional wound dressings
Surgical site infection
Closed incisions
Orthopaedic trauma
Meta-analysis
url https://doi.org/10.1186/s13018-019-1488-z
work_keys_str_mv AT congwang negativepressurewoundtherapyforclosedincisionsinorthopedictraumasurgeryametaanalysis
AT yiwenzhang negativepressurewoundtherapyforclosedincisionsinorthopedictraumasurgeryametaanalysis
AT haoqu negativepressurewoundtherapyforclosedincisionsinorthopedictraumasurgeryametaanalysis