Aspirin Caused Intestinal Damage through FXR and ET-1 Signaling Pathways

Aspirin Caused Intestinal Damage through FXR and ET-1 Signaling Pathways

Aspirin is a non-steroidal, anti-inflammatory drug often used long term. However, long-term or large doses will cause gastrointestinal adverse reactions. To explore the mechanism of intestinal damage, we used non-targeted metabolomics; farnesoid X receptor (FXR) knockout mice, which were compared wi...

Full description

Bibliographic Details
Main Authors: Qiuxia Lin, Binbin Zhang, Manyun Dai, Yan Cheng, Fei Li
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
aspirin
intestinal injury
FXR
endothelin 1
bile acid
Online Access:https://www.mdpi.com/1422-0067/25/6/3424

Similar Items

Similar Items