Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity

Clustered ion channels at nodes of Ranvier are critical for fast action potential propagation in myelinated axons. Axon-glia interactions converge on ankyrin and spectrin cytoskeletal proteins to cluster nodal Na+ channels during development. However, how nodal ion channel clusters are maintained is...

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Бібліографічні деталі
Автори: Cheng-Hsin Liu, Sharon R Stevens, Lindsay H Teliska, Michael Stankewich, Peter J Mohler, Thomas J Hund, Matthew N Rasband
Формат: Стаття
Мова:English
Опубліковано: eLife Sciences Publications Ltd 2020-02-01
Серія:eLife
Предмети:
Онлайн доступ:https://elifesciences.org/articles/52378