Characterization of the mIF4G Domains in the RNA Surveillance Protein Upf2p

Thirty percent of all mutations causing human disease generate mRNAs with premature termination codons (PTCs). Recognition and degradation of these PTC-containing mRNAs is carried out by the mechanism known as nonsense-mediated mRNA decay (NMD). Upf2 is a scaffold protein known to be a central compo...

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Detalles Bibliográficos
Autores principales: Edgardo M. Colón, Luis A. Haddock, Clarivel Lasalde, Qishan Lin, Juan S. Ramírez-Lugo, Carlos I. González
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2023-12-01
Colección:Current Issues in Molecular Biology
Materias:
Acceso en línea:https://www.mdpi.com/1467-3045/46/1/17