Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging
Purpose To develop and validate a three-dimensional (3-D) computer model based on accurate geometry of an irrigated cardiac radiofrequency (RF) ablation catheter with microwave radiometry capability, and to test catheter performance. Methods A computer model was developed based on CAD geometry of a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | http://dx.doi.org/10.1080/02656736.2021.1961027 |
| _version_ | 1818967591343882240 |
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| author | Christian Rossmann Anjan Motamarry Dorin Panescu Dieter Haemmerich |
| author_facet | Christian Rossmann Anjan Motamarry Dorin Panescu Dieter Haemmerich |
| author_sort | Christian Rossmann |
| collection | DOAJ |
| description | Purpose To develop and validate a three-dimensional (3-D) computer model based on accurate geometry of an irrigated cardiac radiofrequency (RF) ablation catheter with microwave radiometry capability, and to test catheter performance. Methods A computer model was developed based on CAD geometry of a RF cardiac ablation catheter prototype to simulate electromagnetic heating, heat transfer, and computational fluid dynamics (blood flow, open irrigation, and natural convection). Parametric studies were performed; blood flow velocity (0–25 cm/s) and irrigation flow (0–40 ml/min) varied, both with perpendicular (PE) and parallel (PA) catheter orientations relative to tissue. Tissue Agar phantom studies were performed under similar conditions, and temperature maps were recorded via infrared camera. Computer model simulations were performed with constant voltage and with voltage adjusted to achieve maximum tissue temperatures of 95–105 °C. Results Model predicted thermal lesion width at 5 W power was 5.8–6.4 mm (PE)/6.5–6.6 mm (PA), and lesion depth was 4.0–4.3 mm (PE)/4.0–4.1 mm (PA). Compared to phantom studies, the mean errors of the computer model were as follows: 6.2 °C(PE)/4.3 °C (PA) for maximum gel temperature, 0.7 mm (10.9%) (PE)/0.1 mm (0.8%) (PA) for lesion width, and 0.3 mm (7.7%)(PE)/0.7 mm (19.1%) (PA) for lesion depth. For temperature-controlled ablation, model predicted thermal lesion width was 7–9.2 mm (PE)/8.6–9.2 mm (PA), and lesion depth was 4.3–5.5 mm (PE)/3.4–5.4 mm (PA). Conclusions Computer models were able to reproduce device performance and to enable device evaluation under varying conditions. Temperature controlled ablation of irrigated catheters enables optimal tissue temperatures independent of patient-specific conditions such as blood flow. |
| first_indexed | 2024-12-20T13:51:14Z |
| format | Article |
| id | doaj.art-8c25b94851b34ffdabd322df2553ecb2 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-12-20T13:51:14Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-8c25b94851b34ffdabd322df2553ecb22022-12-21T19:38:30ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572021-01-013811149116310.1080/02656736.2021.19610271961027Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imagingChristian Rossmann0Anjan Motamarry1Dorin Panescu2Dieter Haemmerich3Department of Pediatrics, Medical University of South CarolinaDepartment of Pediatrics, Medical University of South CarolinaBiotronikDepartment of Pediatrics, Medical University of South CarolinaPurpose To develop and validate a three-dimensional (3-D) computer model based on accurate geometry of an irrigated cardiac radiofrequency (RF) ablation catheter with microwave radiometry capability, and to test catheter performance. Methods A computer model was developed based on CAD geometry of a RF cardiac ablation catheter prototype to simulate electromagnetic heating, heat transfer, and computational fluid dynamics (blood flow, open irrigation, and natural convection). Parametric studies were performed; blood flow velocity (0–25 cm/s) and irrigation flow (0–40 ml/min) varied, both with perpendicular (PE) and parallel (PA) catheter orientations relative to tissue. Tissue Agar phantom studies were performed under similar conditions, and temperature maps were recorded via infrared camera. Computer model simulations were performed with constant voltage and with voltage adjusted to achieve maximum tissue temperatures of 95–105 °C. Results Model predicted thermal lesion width at 5 W power was 5.8–6.4 mm (PE)/6.5–6.6 mm (PA), and lesion depth was 4.0–4.3 mm (PE)/4.0–4.1 mm (PA). Compared to phantom studies, the mean errors of the computer model were as follows: 6.2 °C(PE)/4.3 °C (PA) for maximum gel temperature, 0.7 mm (10.9%) (PE)/0.1 mm (0.8%) (PA) for lesion width, and 0.3 mm (7.7%)(PE)/0.7 mm (19.1%) (PA) for lesion depth. For temperature-controlled ablation, model predicted thermal lesion width was 7–9.2 mm (PE)/8.6–9.2 mm (PA), and lesion depth was 4.3–5.5 mm (PE)/3.4–5.4 mm (PA). Conclusions Computer models were able to reproduce device performance and to enable device evaluation under varying conditions. Temperature controlled ablation of irrigated catheters enables optimal tissue temperatures independent of patient-specific conditions such as blood flow.http://dx.doi.org/10.1080/02656736.2021.1961027radiofrequency/microwavethermal ablationcardiac catheter ablationmodeling (i.e.heat transferultrasoundemintegratedtreatment planning) |
| spellingShingle | Christian Rossmann Anjan Motamarry Dorin Panescu Dieter Haemmerich Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging International Journal of Hyperthermia radiofrequency/microwave thermal ablation cardiac catheter ablation modeling (i.e. heat transfer ultrasound em integrated treatment planning) |
| title | Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging |
| title_full | Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging |
| title_fullStr | Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging |
| title_full_unstemmed | Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging |
| title_short | Computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging |
| title_sort | computer simulations of an irrigated radiofrequency cardiac ablation catheter and experimental validation by infrared imaging |
| topic | radiofrequency/microwave thermal ablation cardiac catheter ablation modeling (i.e. heat transfer ultrasound em integrated treatment planning) |
| url | http://dx.doi.org/10.1080/02656736.2021.1961027 |
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