Single nucleotide mutation changes the capability of CCN3 in osteosarcoma cell invasion and differentiation

Single nucleotide mutation changes the capability of CCN3 in osteosarcoma cell invasion and differentiation

This study aimed to identify significant mutations in CCN3 gene in osteosarcoma, and to explore the influence of this gene on cell invasion and differentiation and the underlying mechanism. Sanger sequencing was used to identify CCN3 gene sequence in human osteosarcoma cell lines, peripheral blood m...

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Bibliographic Details
Main Authors: Xuejing Yan, Wei Yan, Xin Fu, Yuqiao Xu, Ning Zhu, Chuan Qiu, Mengmeng Bu, Yan Shen, Meihong Chen
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Translational Oncology
Subjects:
CCN3
Mutation
Osteosarcoma
Invasion
Differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322001449

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