2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine

A simple method for the synthesis of a pyrazolyl thiazole derivative containing a piperonal moiety was developed. Thus, 2-{5-(1,3-benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine was synthesized using microwave irradiation and characterized by NMR, IR an...

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Main Authors: Suban Syed Shafi, Sriram Narasimhan, Balapragalathan Thappali Jothikrishnan
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Molbank
Subjects:
Online Access:http://www.mdpi.com/1422-8599/2010/1/M668/
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author Suban Syed Shafi
Sriram Narasimhan
Balapragalathan Thappali Jothikrishnan
author_facet Suban Syed Shafi
Sriram Narasimhan
Balapragalathan Thappali Jothikrishnan
author_sort Suban Syed Shafi
collection DOAJ
description A simple method for the synthesis of a pyrazolyl thiazole derivative containing a piperonal moiety was developed. Thus, 2-{5-(1,3-benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine was synthesized using microwave irradiation and characterized by NMR, IR and LCMS data.
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spelling doaj.art-8c29ac2b75334dcd8b7c47806ef9de202022-12-21T19:59:49ZengMDPI AGMolbank1422-85992010-03-0120101M66810.3390/M6682-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazineSuban Syed ShafiSriram NarasimhanBalapragalathan Thappali JothikrishnanA simple method for the synthesis of a pyrazolyl thiazole derivative containing a piperonal moiety was developed. Thus, 2-{5-(1,3-benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine was synthesized using microwave irradiation and characterized by NMR, IR and LCMS data.http://www.mdpi.com/1422-8599/2010/1/M668/5-(1,3-benzodioxol-5-yl)-3-(pyrazin-2-yl)-4,5-dihydro-1H-pyrazole-1-carbo-thioamide4-chlorophenacyl bromidemicrowave
spellingShingle Suban Syed Shafi
Sriram Narasimhan
Balapragalathan Thappali Jothikrishnan
2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
Molbank
5-(1,3-benzodioxol-5-yl)-3-(pyrazin-2-yl)-4,5-dihydro-1H-pyrazole-1-carbo-thioamide
4-chlorophenacyl bromide
microwave
title 2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
title_full 2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
title_fullStr 2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
title_full_unstemmed 2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
title_short 2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
title_sort 2 5 1 3 benzodioxol 5 yl 1 4 4 chlorophenyl 1 3 thiazol 2 yl 4 5 dihydro 1h pyrazol 3 yl pyrazine
topic 5-(1,3-benzodioxol-5-yl)-3-(pyrazin-2-yl)-4,5-dihydro-1H-pyrazole-1-carbo-thioamide
4-chlorophenacyl bromide
microwave
url http://www.mdpi.com/1422-8599/2010/1/M668/
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AT sriramnarasimhan 2513benzodioxol5yl144chlorophenyl13thiazol2yl45dihydro1hpyrazol3ylpyrazine
AT balapragalathanthappalijothikrishnan 2513benzodioxol5yl144chlorophenyl13thiazol2yl45dihydro1hpyrazol3ylpyrazine