Histopathological assessment of experimental acute sinusitis in rabbit
Objectives:In this study, investigation of the histopathologic and microbiologic changes in acute sinusitis was aimed and animal model was planned accordingly.Methods:This study was conducted by rhinogenic method using Streptococcus pneumoniae type 14. On one side of the nasal cavities of the twenty...
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| Format: | Article |
| Language: | English |
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Galenos Yayincilik
2005-12-01
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| Series: | Turkish Archives of Otorhinolaryngology |
| Subjects: | |
| Online Access: |
http://turkarchotolaryngol.net/archives/archive-detail/article-preview/histopathological-assessment-of-experimental-acute/43648
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| _version_ | 1797911393889943552 |
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| author | Abdülkadir Bucak Mustafa Kuzdere Bennur Çetindağ Şenol Baş |
| author_facet | Abdülkadir Bucak Mustafa Kuzdere Bennur Çetindağ Şenol Baş |
| author_sort | Abdülkadir Bucak |
| collection | DOAJ |
| description | Objectives:In this study, investigation of the histopathologic and microbiologic changes in acute sinusitis was aimed and animal model was planned accordingly.Methods:This study was conducted by rhinogenic method using Streptococcus pneumoniae type 14. On one side of the nasal cavities of the twenty New Zealand rabbits, a foreign body impregnated with serum physiologic and on the other side a foreign body impregnated with bacteria were placed and afterwards, the sacrification of 5 animals weekly was planned. Both histopathologic and microbiologic assessment was applied to the both side of the nasal and paranasal sinuses to all of the sample animals.Results:In histopathologic evaluation of the first two weeks, neutrophil leucocyts, rare lymphocyts and plasma cells were seen on mucosal and submucosal tissue. However, in the third and fourth weeks, an intensive increase in lymphocyts and plasma cells was observed. In bacteriologic investigation apart from Streptococcus pneumoniae, E. coli, beta-hemolytic streptococcus, Staphylococcus aureus were identified.Conclusion:Histopathologically generated sinusitis in all of the animals and the histopathological conclusions were consistent with the natural prognosis of the infection and literature information. |
| first_indexed | 2024-04-10T11:39:44Z |
| format | Article |
| id | doaj.art-8c2b2d6335284ac8b126008708643bf4 |
| institution | Directory Open Access Journal |
| issn | 2667-7474 |
| language | English |
| last_indexed | 2024-04-10T11:39:44Z |
| publishDate | 2005-12-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | Turkish Archives of Otorhinolaryngology |
| spelling | doaj.art-8c2b2d6335284ac8b126008708643bf42023-02-15T16:17:35ZengGalenos YayincilikTurkish Archives of Otorhinolaryngology2667-74742005-12-0143420721413049054Histopathological assessment of experimental acute sinusitis in rabbitAbdülkadir Bucak0Mustafa Kuzdere1Bennur Çetindağ2Şenol Baş3 SSK Afyon Hastanesi Kulak Burun Boğaz Kliniği, Afyonkarahisar SSK Okmeydanı Eğitim Hastanesi Kulak Burun Boğaz ve Bafl Boyun Cerrahisi Kliniği, İstanbul SSK Okmeydanı Eğitim Hastanesi Kulak Burun Boğaz ve Bafl Boyun Cerrahisi Kliniği, İstanbul SSK Okmeydanı Eğitim Hastanesi Kulak Burun Boğaz ve Bafl Boyun Cerrahisi Kliniği, İstanbul Objectives:In this study, investigation of the histopathologic and microbiologic changes in acute sinusitis was aimed and animal model was planned accordingly.Methods:This study was conducted by rhinogenic method using Streptococcus pneumoniae type 14. On one side of the nasal cavities of the twenty New Zealand rabbits, a foreign body impregnated with serum physiologic and on the other side a foreign body impregnated with bacteria were placed and afterwards, the sacrification of 5 animals weekly was planned. Both histopathologic and microbiologic assessment was applied to the both side of the nasal and paranasal sinuses to all of the sample animals.Results:In histopathologic evaluation of the first two weeks, neutrophil leucocyts, rare lymphocyts and plasma cells were seen on mucosal and submucosal tissue. However, in the third and fourth weeks, an intensive increase in lymphocyts and plasma cells was observed. In bacteriologic investigation apart from Streptococcus pneumoniae, E. coli, beta-hemolytic streptococcus, Staphylococcus aureus were identified.Conclusion:Histopathologically generated sinusitis in all of the animals and the histopathological conclusions were consistent with the natural prognosis of the infection and literature information. http://turkarchotolaryngol.net/archives/archive-detail/article-preview/histopathological-assessment-of-experimental-acute/43648 histopathologyacute sinusitisrhinogenic methodrabbit. |
| spellingShingle | Abdülkadir Bucak Mustafa Kuzdere Bennur Çetindağ Şenol Baş Histopathological assessment of experimental acute sinusitis in rabbit Turkish Archives of Otorhinolaryngology histopathology acute sinusitis rhinogenic method rabbit. |
| title | Histopathological assessment of experimental acute sinusitis in rabbit |
| title_full | Histopathological assessment of experimental acute sinusitis in rabbit |
| title_fullStr | Histopathological assessment of experimental acute sinusitis in rabbit |
| title_full_unstemmed | Histopathological assessment of experimental acute sinusitis in rabbit |
| title_short | Histopathological assessment of experimental acute sinusitis in rabbit |
| title_sort | histopathological assessment of experimental acute sinusitis in rabbit |
| topic | histopathology acute sinusitis rhinogenic method rabbit. |
| url |
http://turkarchotolaryngol.net/archives/archive-detail/article-preview/histopathological-assessment-of-experimental-acute/43648
|
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