Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers
A rare sub-population of people living with HIV-1 experience long-lasting viral remission after interrupting antiretroviral therapy and are considered post-treatment controllers. Here the authors characterise the humoral immune response to HIV-1 in a cohort of post-treatment controllers.
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-29511-1 |
| _version_ | 1828847709855940608 |
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| author | Luis M. Molinos-Albert Valérie Lorin Valérie Monceaux Sylvie Orr Asma Essat Jérémy Dufloo Olivier Schwartz Christine Rouzioux Laurence Meyer Laurent Hocqueloux Asier Sáez-Cirión Hugo Mouquet ANRS VISCONTI Study Group |
| author_facet | Luis M. Molinos-Albert Valérie Lorin Valérie Monceaux Sylvie Orr Asma Essat Jérémy Dufloo Olivier Schwartz Christine Rouzioux Laurence Meyer Laurent Hocqueloux Asier Sáez-Cirión Hugo Mouquet ANRS VISCONTI Study Group |
| author_sort | Luis M. Molinos-Albert |
| collection | DOAJ |
| description | A rare sub-population of people living with HIV-1 experience long-lasting viral remission after interrupting antiretroviral therapy and are considered post-treatment controllers. Here the authors characterise the humoral immune response to HIV-1 in a cohort of post-treatment controllers. |
| first_indexed | 2024-12-12T22:14:35Z |
| format | Article |
| id | doaj.art-8c2bb6fda8ec43b2afd6cfd0349d774c |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-12T22:14:35Z |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-8c2bb6fda8ec43b2afd6cfd0349d774c2022-12-22T00:10:07ZengNature PortfolioNature Communications2041-17232022-04-0113111710.1038/s41467-022-29511-1Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllersLuis M. Molinos-Albert0Valérie Lorin1Valérie Monceaux2Sylvie Orr3Asma Essat4Jérémy Dufloo5Olivier Schwartz6Christine Rouzioux7Laurence Meyer8Laurent Hocqueloux9Asier Sáez-Cirión10Hugo Mouquet11ANRS VISCONTI Study GroupLaboratory of Humoral Immunology, Department of Immunology, Institut Pasteur, Université Paris CitéLaboratory of Humoral Immunology, Department of Immunology, Institut Pasteur, Université Paris CitéHIV, Inflammation and Persistence Unit, Department of Virology, Institut Pasteur, Université Paris CitéCentre de Recherche en Epidémiologie et Santé des Populations (CESP), Université Paris-Sud, Université Paris-Saclay, INSERMCentre de Recherche en Epidémiologie et Santé des Populations (CESP), Université Paris-Sud, Université Paris-Saclay, INSERMVirus & Immunity Unit, Department of Virology, Institut Pasteur, Université Paris Cité and CNRS UMR3569Virus & Immunity Unit, Department of Virology, Institut Pasteur, Université Paris Cité and CNRS UMR3569Assistance Publique-Hôpitaux de Paris, Service de Microbiologie Clinique, Hôpital Necker-Enfants MaladesCentre de Recherche en Epidémiologie et Santé des Populations (CESP), Université Paris-Sud, Université Paris-Saclay, INSERMService des Maladies Infectieuses et Tropicales, CHR d’Orléans-La SourceHIV, Inflammation and Persistence Unit, Department of Virology, Institut Pasteur, Université Paris CitéLaboratory of Humoral Immunology, Department of Immunology, Institut Pasteur, Université Paris CitéA rare sub-population of people living with HIV-1 experience long-lasting viral remission after interrupting antiretroviral therapy and are considered post-treatment controllers. Here the authors characterise the humoral immune response to HIV-1 in a cohort of post-treatment controllers.https://doi.org/10.1038/s41467-022-29511-1 |
| spellingShingle | Luis M. Molinos-Albert Valérie Lorin Valérie Monceaux Sylvie Orr Asma Essat Jérémy Dufloo Olivier Schwartz Christine Rouzioux Laurence Meyer Laurent Hocqueloux Asier Sáez-Cirión Hugo Mouquet ANRS VISCONTI Study Group Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers Nature Communications |
| title | Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers |
| title_full | Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers |
| title_fullStr | Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers |
| title_full_unstemmed | Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers |
| title_short | Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers |
| title_sort | transient viral exposure drives functionally coordinated humoral immune responses in hiv 1 post treatment controllers |
| url | https://doi.org/10.1038/s41467-022-29511-1 |
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