The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways
Cardiac remodeling is defined as molecular, cellular, and interstitial changes that manifest clinically as alterations in the size, shape, and function of the heart. Despite the pharmacological approaches, cardiac remodeling-related mortality rates remain high. Therefore, other therapeutic options a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-12-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/12/12/2067 |
| _version_ | 1797382249962799104 |
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| author | Taline Lazzarin Danilo Martins Raquel S. Ballarin Marina G. Monte Marcos F. Minicucci Bertha F. Polegato Leonardo Zornoff |
| author_facet | Taline Lazzarin Danilo Martins Raquel S. Ballarin Marina G. Monte Marcos F. Minicucci Bertha F. Polegato Leonardo Zornoff |
| author_sort | Taline Lazzarin |
| collection | DOAJ |
| description | Cardiac remodeling is defined as molecular, cellular, and interstitial changes that manifest clinically as alterations in the size, shape, and function of the heart. Despite the pharmacological approaches, cardiac remodeling-related mortality rates remain high. Therefore, other therapeutic options are being increasingly studied. This review highlights the role of omega-3 as an adjunctive therapy to attenuate cardiac remodeling, with an emphasis on its antioxidant and anti-inflammatory actions. |
| first_indexed | 2024-03-08T21:02:44Z |
| format | Article |
| id | doaj.art-8c35737a72294787bb136c5a9c6157b4 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-08T21:02:44Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-8c35737a72294787bb136c5a9c6157b42023-12-22T13:48:24ZengMDPI AGAntioxidants2076-39212023-12-011212206710.3390/antiox12122067The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation PathwaysTaline Lazzarin0Danilo Martins1Raquel S. Ballarin2Marina G. Monte3Marcos F. Minicucci4Bertha F. Polegato5Leonardo Zornoff6Internal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilInternal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilInternal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilInternal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilInternal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilInternal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilInternal Medicine Department, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18600-000, BrazilCardiac remodeling is defined as molecular, cellular, and interstitial changes that manifest clinically as alterations in the size, shape, and function of the heart. Despite the pharmacological approaches, cardiac remodeling-related mortality rates remain high. Therefore, other therapeutic options are being increasingly studied. This review highlights the role of omega-3 as an adjunctive therapy to attenuate cardiac remodeling, with an emphasis on its antioxidant and anti-inflammatory actions.https://www.mdpi.com/2076-3921/12/12/2067oxidative stresscardiac failureremodelingfatty acidsomega-3 |
| spellingShingle | Taline Lazzarin Danilo Martins Raquel S. Ballarin Marina G. Monte Marcos F. Minicucci Bertha F. Polegato Leonardo Zornoff The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways Antioxidants oxidative stress cardiac failure remodeling fatty acids omega-3 |
| title | The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways |
| title_full | The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways |
| title_fullStr | The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways |
| title_full_unstemmed | The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways |
| title_short | The Role of Omega-3 in Attenuating Cardiac Remodeling and Heart Failure through the Oxidative Stress and Inflammation Pathways |
| title_sort | role of omega 3 in attenuating cardiac remodeling and heart failure through the oxidative stress and inflammation pathways |
| topic | oxidative stress cardiac failure remodeling fatty acids omega-3 |
| url | https://www.mdpi.com/2076-3921/12/12/2067 |
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