Silybin Showed Higher Cytotoxic, Antiproliferative, and Anti-Inflammatory Activities in the CaCo Cancer Cell Line while Retaining Viability and Proliferation in Normal Intestinal IPEC-1 Cells

The anticancer potential of silymarin is well known, including its anti-inflammatory as well as antiproliferative effect mediated by influencing the cell cycle, suppression of apoptosis, and inhibition of cell-survival kinases. However, less is known about silybin, the main component of the silymari...

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Main Authors: Dominika Faixová, Marek Ratvaj, Ivana Cingeľová Maruščáková, Gabriela Hrčková, Viera Karaffová, Zita Faixová, Dagmar Mudroňová
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/2/492