Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection

The article presents the clinical case data, demonstra-ting the difficulties in clarifying the origin of the disease in a young child. Difficulty of diagnosis is caused by the lack of specific clinical manifestations of the disease. The diagnosis of streptococcal infection in this girl was establish...

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Main Author: T.O. Kirsanova
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2015-04-01
Series:Aktualʹnaâ Infektologiâ
Subjects:
Online Access:http://ai.zaslavsky.com.ua/article/view/78622
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author T.O. Kirsanova
author_facet T.O. Kirsanova
author_sort T.O. Kirsanova
collection DOAJ
description The article presents the clinical case data, demonstra-ting the difficulties in clarifying the origin of the disease in a young child. Difficulty of diagnosis is caused by the lack of specific clinical manifestations of the disease. The diagnosis of streptococcal infection in this girl was established on the basis of intoxication symptoms, post-nasal drip, detecting S.pyogenes in high titre at bacteriological test of mucus from the nasal and oropharynx, as well as the absence of antibodies to other bacterial and viral agents in the child. The persistence of Streptococcus has been shown by the duration of the clinical manifestations of the disease of more than 2 months. Given the long persistence in the body of the child of β-hemolytic streptococcus and the presence among its factors of M-protein virulence and thermostable fraction of erythrogenic toxin, which are the triggers of toxic and allergic pathological process, persistent streptococcal infection resulted in the development of allergic sepsis (Wissler — Fanconi subsepsis).
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spelling doaj.art-8c3d63a26d934b1ab81ada4abf3473392022-12-21T17:17:12ZengZaslavsky O.Yu.Aktualʹnaâ Infektologiâ2312-413X2312-41482015-04-0132.07636710.22141/2312-413x.2.07.2015.7862278622Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal InfectionT.O. Kirsanova0Kharkiv National Medical University, KharkivThe article presents the clinical case data, demonstra-ting the difficulties in clarifying the origin of the disease in a young child. Difficulty of diagnosis is caused by the lack of specific clinical manifestations of the disease. The diagnosis of streptococcal infection in this girl was established on the basis of intoxication symptoms, post-nasal drip, detecting S.pyogenes in high titre at bacteriological test of mucus from the nasal and oropharynx, as well as the absence of antibodies to other bacterial and viral agents in the child. The persistence of Streptococcus has been shown by the duration of the clinical manifestations of the disease of more than 2 months. Given the long persistence in the body of the child of β-hemolytic streptococcus and the presence among its factors of M-protein virulence and thermostable fraction of erythrogenic toxin, which are the triggers of toxic and allergic pathological process, persistent streptococcal infection resulted in the development of allergic sepsis (Wissler — Fanconi subsepsis).http://ai.zaslavsky.com.ua/article/view/78622childrenstreptococcal infectionWissler — Fanconi subsepsis
spellingShingle T.O. Kirsanova
Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
Aktualʹnaâ Infektologiâ
children
streptococcal infection
Wissler — Fanconi subsepsis
title Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
title_full Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
title_fullStr Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
title_full_unstemmed Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
title_short Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
title_sort wissler fanconi subsepsis as a result of persistent streptococcal infection
topic children
streptococcal infection
Wissler — Fanconi subsepsis
url http://ai.zaslavsky.com.ua/article/view/78622
work_keys_str_mv AT tokirsanova wisslerfanconisubsepsisasaresultofpersistentstreptococcalinfection