Insights Into Parkin-Mediated Mitophagy in Alzheimer's Disease: A Systematic Review

Insights Into Parkin-Mediated Mitophagy in Alzheimer's Disease: A Systematic Review

Background: Parkin-mediated mitophagy is the dominant mitophagy pathway of neural cells. Its restoration will result in prevention of cognitive decline, including Alzheimer's disease (AD). The role of this mitophagy pathway in neurodegenerative diseases has drawn attention in recent years. The...

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Bibliographic Details
Main Authors: Sepideh Goudarzi, Asieh Hosseini, Mohammad Abdollahi, Hamed Haghi-Aminjan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
amyloid–beta
mitophagy
PINK 1
Parkin (PARK2)
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.674071/full

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