Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis
Calcium (Ca2+)-evoked release of neurotransmitters from synaptic vesicles requires mechanisms both to prevent un-initiated fusion of vesicles (clamping) and to trigger fusion following Ca2+-influx. The principal components involved in these processes are the vesicular fusion machinery (SNARE protein...
Main Authors: | Sathish Ramakrishnan, Manindra Bera, Jeff Coleman, James E Rothman, Shyam S Krishnakumar |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/54506 |
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