Circular single-stranded DNA as switchable vector for gene expression in mammalian cells
Abstract Synthetic gene networks in mammalian cells are currently limited to either protein-based transcription factors or RNA-based regulators. Here, we demonstrate a regulatory approach based on circular single-stranded DNA (Css DNA), which can be used as an efficient expression vector with switch...
| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
Nature Portfolio
2023-10-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-023-42437-6 |