Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research

The aim of this qualitative systematic review is to analyze the barriers and facilitators to the uptake of antihypertensive medication in hypertensive patients. The databases of PubMed, Embase, Web of Science, CINAHL, Cochrane Library, MEDLINE, China National Knowledge Infrastructure, Wanfang, VIP,...

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Main Authors: Xueying Zhou MS, Xuefang Zhang PhD, Ning Gu MD, Wenjing Cai MS, Jingyi Feng MS
Format: Article
Language:English
Published: SAGE Publishing 2024-03-01
Series:Journal of Patient Experience
Online Access:https://doi.org/10.1177/23743735241241176
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author Xueying Zhou MS
Xuefang Zhang PhD
Ning Gu MD
Wenjing Cai MS
Jingyi Feng MS
author_facet Xueying Zhou MS
Xuefang Zhang PhD
Ning Gu MD
Wenjing Cai MS
Jingyi Feng MS
author_sort Xueying Zhou MS
collection DOAJ
description The aim of this qualitative systematic review is to analyze the barriers and facilitators to the uptake of antihypertensive medication in hypertensive patients. The databases of PubMed, Embase, Web of Science, CINAHL, Cochrane Library, MEDLINE, China National Knowledge Infrastructure, Wanfang, VIP, and Chinese Biomedical were searched from inception to June 2023. The studies were screened, extracted, and assessed independently by two researchers. Previously, the researchers used the Joanna Briggs Institute Critical Appraisal Checklist for Qualitative Research to assess the quality of the included studies. A total of 27 studies were considered, resulting in two combined findings: a good level of knowledge, belief, and behavior and adequate social support were facilitators of medication adherence in hypertensive patients. In contrast, lack of medication literacy, difficulty adapting to roles, reduced sense of benefit from treatment, limited access to healthcare resources, and unintentional nonadherence were barriers. Medication adherence in hypertensive patients remains a challenge to be addressed. Future research should explore how complex interventions using a combination of evidence-based strategies and targeting multiple adherence behaviors (eg, long-term adherence to medication) are effective in improving medication adherence.
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spelling doaj.art-8c4839ac33c840f69b5913761852b7112024-03-27T13:03:52ZengSAGE PublishingJournal of Patient Experience2374-37432024-03-011110.1177/23743735241241176Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative ResearchXueying Zhou MS0Xuefang Zhang PhD1Ning Gu MD2Wenjing Cai MS3Jingyi Feng MS4 School of Nursing, , Nanjing, Jiangsu Province, China Quality Management Office, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu Province, China Department of Cardiology, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu Province, China School of Nursing, , Nanjing, Jiangsu Province, China School of Nursing, , Nanjing, Jiangsu Province, ChinaThe aim of this qualitative systematic review is to analyze the barriers and facilitators to the uptake of antihypertensive medication in hypertensive patients. The databases of PubMed, Embase, Web of Science, CINAHL, Cochrane Library, MEDLINE, China National Knowledge Infrastructure, Wanfang, VIP, and Chinese Biomedical were searched from inception to June 2023. The studies were screened, extracted, and assessed independently by two researchers. Previously, the researchers used the Joanna Briggs Institute Critical Appraisal Checklist for Qualitative Research to assess the quality of the included studies. A total of 27 studies were considered, resulting in two combined findings: a good level of knowledge, belief, and behavior and adequate social support were facilitators of medication adherence in hypertensive patients. In contrast, lack of medication literacy, difficulty adapting to roles, reduced sense of benefit from treatment, limited access to healthcare resources, and unintentional nonadherence were barriers. Medication adherence in hypertensive patients remains a challenge to be addressed. Future research should explore how complex interventions using a combination of evidence-based strategies and targeting multiple adherence behaviors (eg, long-term adherence to medication) are effective in improving medication adherence.https://doi.org/10.1177/23743735241241176
spellingShingle Xueying Zhou MS
Xuefang Zhang PhD
Ning Gu MD
Wenjing Cai MS
Jingyi Feng MS
Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research
Journal of Patient Experience
title Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research
title_full Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research
title_fullStr Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research
title_full_unstemmed Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research
title_short Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research
title_sort barriers and facilitators of medication adherence in hypertension patients a meta integration of qualitative research
url https://doi.org/10.1177/23743735241241176
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