Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars
Primary failure of eruption (PFE) is a rare non-syndromic condition involving total or partial non-eruption of posterior teeth in the absence of mechanical obstruction. This paper presents the case of a healthy girl referred at age 4 for asymmetry of the upper arch. Clinical examination confirmed a...
| 主要な著者: | , , , |
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| フォーマット: | 論文 |
| 言語: | English |
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MDPI AG
2024-01-01
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| シリーズ: | Children |
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| オンライン･アクセス: | https://www.mdpi.com/2227-9067/11/2/152 |
| _version_ | 1827343874024013824 |
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| author | Arina Vinereanu Aneta Munteanu Francois Clauss Eusebiu Vlad Gorduza |
| author_facet | Arina Vinereanu Aneta Munteanu Francois Clauss Eusebiu Vlad Gorduza |
| author_sort | Arina Vinereanu |
| collection | DOAJ |
| description | Primary failure of eruption (PFE) is a rare non-syndromic condition involving total or partial non-eruption of posterior teeth in the absence of mechanical obstruction. This paper presents the case of a healthy girl referred at age 4 for asymmetry of the upper arch. Clinical examination confirmed a slight shift of the upper midline to the left, with no erupted teeth distal to the upper left canine and a left posterior open bite. Panoramic X-rays showed delayed intraosseous development of the lateral left upper teeth compared to the right side. Clinic and radiographic follow-up during the next 9 years showed that 26 had not erupted by almost 13 years of age, 27 had delayed development and an unusual shape, and there was an agenesis in 24 and 25. Genetic analysis using the <i>PTH1R</i> single-gene sequencing method did not detect any known disease-causing or rare pathogenic variants that could explain the patient’s phenotype. Even when detected early, PFE raises difficult problems with regard to diagnosis and ortho-surgical treatment planning due to the impossibility of accurately predicting its evolution. Tooth agenesis on the same arch worsens the prognosis and adds challenges to planning the treatment. Close long-term follow-up and timely adjustment of the treatment plan in accordance with the evolution of the case are needed. |
| first_indexed | 2024-03-07T22:37:47Z |
| format | Article |
| id | doaj.art-8c4a2667e3cd440d9c151171a0423d7a |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-07T22:37:47Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-8c4a2667e3cd440d9c151171a0423d7a2024-02-23T15:12:12ZengMDPI AGChildren2227-90672024-01-0111215210.3390/children11020152Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of PremolarsArina Vinereanu0Aneta Munteanu1Francois Clauss2Eusebiu Vlad Gorduza3Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Dental Surgery, University of Strasbourg, 67081 Strasbourg, FranceFaculty of Medicine, Grigore. T. Popa University of Medicine and Pharmacy Iași, 700115 Iași, RomaniaPrimary failure of eruption (PFE) is a rare non-syndromic condition involving total or partial non-eruption of posterior teeth in the absence of mechanical obstruction. This paper presents the case of a healthy girl referred at age 4 for asymmetry of the upper arch. Clinical examination confirmed a slight shift of the upper midline to the left, with no erupted teeth distal to the upper left canine and a left posterior open bite. Panoramic X-rays showed delayed intraosseous development of the lateral left upper teeth compared to the right side. Clinic and radiographic follow-up during the next 9 years showed that 26 had not erupted by almost 13 years of age, 27 had delayed development and an unusual shape, and there was an agenesis in 24 and 25. Genetic analysis using the <i>PTH1R</i> single-gene sequencing method did not detect any known disease-causing or rare pathogenic variants that could explain the patient’s phenotype. Even when detected early, PFE raises difficult problems with regard to diagnosis and ortho-surgical treatment planning due to the impossibility of accurately predicting its evolution. Tooth agenesis on the same arch worsens the prognosis and adds challenges to planning the treatment. Close long-term follow-up and timely adjustment of the treatment plan in accordance with the evolution of the case are needed.https://www.mdpi.com/2227-9067/11/2/152primary failure of eruptionpremolar agenesiscase report |
| spellingShingle | Arina Vinereanu Aneta Munteanu Francois Clauss Eusebiu Vlad Gorduza Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars Children primary failure of eruption premolar agenesis case report |
| title | Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars |
| title_full | Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars |
| title_fullStr | Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars |
| title_full_unstemmed | Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars |
| title_short | Rare Case of First Permanent Molar Primary Failure of Eruption with Agenesis of Premolars |
| title_sort | rare case of first permanent molar primary failure of eruption with agenesis of premolars |
| topic | primary failure of eruption premolar agenesis case report |
| url | https://www.mdpi.com/2227-9067/11/2/152 |
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