N-cadherin in osteolineage cells modulates stromal support of tumor growth

N-cadherin in osteolineage cells modulates stromal support of tumor growth

Tumor growth and metastases are dependent on interactions between cancer cells and the local environment. Expression of the cell–cell adhesion molecule N-cadherin (Ncad) is associated with highly aggressive cancers, and its expression by osteogenic cells has been proposed to provide a molecular “doc...

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Bibliographic Details
Main Authors:	Francesca Fontana, Jingyu Xiang, Xinming Su, Eric Tycksen, Rachel Nassau, Gregory Fox, Giulia Leanza, Katherine Weilbaecher, Roberto Civitelli
Format:	Article
Language:	English
Published:	Elsevier 2021-06-01
Series:	Journal of Bone Oncology
Subjects:	N-cadherin Bone-tumor cell interactions Tumor microenvironment Transcriptomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212137421000105

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