Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations]
Background: Maxillofacial silicones are the most popular and acceptable material for making maxillofacial prostheses, but they are not perfect in every sense. To enhance their effectiveness, more improvements to their properties are required, such as their antimicrobial efficiency. This study assess...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2023-11-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/12-385/v2 |
| _version_ | 1797635422040358912 |
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| author | Thekra Ismael Hamad Yasir Mohammed Kareem |
| author_facet | Thekra Ismael Hamad Yasir Mohammed Kareem |
| author_sort | Thekra Ismael Hamad |
| collection | DOAJ |
| description | Background: Maxillofacial silicones are the most popular and acceptable material for making maxillofacial prostheses, but they are not perfect in every sense. To enhance their effectiveness, more improvements to their properties are required, such as their antimicrobial efficiency. This study assess the antibacterial effect of barium titanate nanoparticles in various percentages against staphylococcus epidermidis biofilm adhesion after addition to maxillofacial silicone. Methods: Barium titanate nanoparticles were added into VST-50 platinum silicone elastomer in four weight percentages (0.25wt%, 0.5wt%, 0.75wt% and 1wt%). 50 specimens were prepared and categorized into five groups; one control group and four experimental groups. All conducted data was statistically analyzed using (one-way ANOVA) analysis of variance, and Games-Howell multiple comparison test (significant level at p < 0.05). Shapiro-Wilk and Levene’s tests were used, respectively, to evaluate the normal distribution and homogeneity of the data. Result: One-way ANOVA test revealed a highly significant difference between all groups, and Games-Howell test revealed a highly significant difference between the control group and the four experimental groups. The 0.25wt% and 0.5wt% groups revealed a highly significant difference between them and with the (0.75%wt and 0.1%wt) groups. While the 0.75wt% group revealed a significant difference with 1wt% group. Conclusions: The addition of barium titanate to VST-50 maxillofacial silicone enhanced the antibacterial activity of silicon against Staphylococcus epidermidis, and this activity seems to be concentration dependent. FTIR analysis demonstrated no chemical interaction between the Barium Titanate and the VST-50 maxillofacial silicone elastomer. SEM pictures show that the barium titanate nanopowder was effectively dispersed inside the maxillofacial silicone matrix. |
| first_indexed | 2024-03-11T12:20:56Z |
| format | Article |
| id | doaj.art-8c5516330fd54fc983958f9fda6c1d64 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-03-11T12:20:56Z |
| publishDate | 2023-11-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-8c5516330fd54fc983958f9fda6c1d642023-11-07T01:00:01ZengF1000 Research LtdF1000Research2046-14022023-11-0112158425Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations]Thekra Ismael Hamad0Yasir Mohammed Kareem1https://orcid.org/0009-0009-5143-1736B.D.S., M.Sc., Ph.D., Prof. Department of Prosthodontic, College of Dentistry, University of Baghdad, Baghdad, Baghdad Governorate, IraqB.D.S. Department of Prosthodontic, College of Dentistry, University of Baghdad, Baghdad, Baghdad Governorate, IraqBackground: Maxillofacial silicones are the most popular and acceptable material for making maxillofacial prostheses, but they are not perfect in every sense. To enhance their effectiveness, more improvements to their properties are required, such as their antimicrobial efficiency. This study assess the antibacterial effect of barium titanate nanoparticles in various percentages against staphylococcus epidermidis biofilm adhesion after addition to maxillofacial silicone. Methods: Barium titanate nanoparticles were added into VST-50 platinum silicone elastomer in four weight percentages (0.25wt%, 0.5wt%, 0.75wt% and 1wt%). 50 specimens were prepared and categorized into five groups; one control group and four experimental groups. All conducted data was statistically analyzed using (one-way ANOVA) analysis of variance, and Games-Howell multiple comparison test (significant level at p < 0.05). Shapiro-Wilk and Levene’s tests were used, respectively, to evaluate the normal distribution and homogeneity of the data. Result: One-way ANOVA test revealed a highly significant difference between all groups, and Games-Howell test revealed a highly significant difference between the control group and the four experimental groups. The 0.25wt% and 0.5wt% groups revealed a highly significant difference between them and with the (0.75%wt and 0.1%wt) groups. While the 0.75wt% group revealed a significant difference with 1wt% group. Conclusions: The addition of barium titanate to VST-50 maxillofacial silicone enhanced the antibacterial activity of silicon against Staphylococcus epidermidis, and this activity seems to be concentration dependent. FTIR analysis demonstrated no chemical interaction between the Barium Titanate and the VST-50 maxillofacial silicone elastomer. SEM pictures show that the barium titanate nanopowder was effectively dispersed inside the maxillofacial silicone matrix.https://f1000research.com/articles/12-385/v2barium titanate (BaTiO3) VST-50 silicone elastomer bacterial adhesion Staphylococcus epidermidis.eng |
| spellingShingle | Thekra Ismael Hamad Yasir Mohammed Kareem Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations] F1000Research barium titanate (BaTiO3) VST-50 silicone elastomer bacterial adhesion Staphylococcus epidermidis. eng |
| title | Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_full | Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_fullStr | Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_full_unstemmed | Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_short | Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_sort | assessment of the antibacterial effect of barium titanate nanoparticles against staphylococcus epidermidis adhesion after addition to maxillofacial silicone version 2 peer review 2 approved 1 approved with reservations |
| topic | barium titanate (BaTiO3) VST-50 silicone elastomer bacterial adhesion Staphylococcus epidermidis. eng |
| url | https://f1000research.com/articles/12-385/v2 |
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